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Aberrant Stress Granule Dynamics and Aggrephagy in ALS Pathogenesis

Stress granules are conserved cytosolic ribonucleoprotein (RNP) compartments that undergo dynamic assembly and disassembly by phase separation in response to stressful conditions. Gene mutations may lead to aberrant phase separation of stress granules eliciting irreversible protein aggregations. A s...

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Detalles Bibliográficos
Autores principales:	Zhang, Yi, Gu, Jiayu, Sun, Qiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468025/ https://www.ncbi.nlm.nih.gov/pubmed/34571896 http://dx.doi.org/10.3390/cells10092247

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