Oxidative Folding of Proteins: The “Smoking Gun” of Glutathione

Glutathione has long been suspected to be the primary low molecular weight compound present in all cells promoting the oxidative protein folding, but twenty years ago it was found “not guilty”. Now, new surprising evidence repeats its request to be the “smoking gun” which reopens the criminal trial...

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Detalles Bibliográficos
Autores principales: Bocedi, Alessio, Cattani, Giada, Gambardella, Giorgia, Schulte, Linda, Schwalbe, Harald, Ricci, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468038/
https://www.ncbi.nlm.nih.gov/pubmed/34576311
http://dx.doi.org/10.3390/ijms221810148
Descripción
Sumario:Glutathione has long been suspected to be the primary low molecular weight compound present in all cells promoting the oxidative protein folding, but twenty years ago it was found “not guilty”. Now, new surprising evidence repeats its request to be the “smoking gun” which reopens the criminal trial revealing the crucial involvement of this tripeptide.

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