Identification of CDK7 Inhibitors from Natural Sources Using Pharmacoinformatics and Molecular Dynamics Simulations

The cyclin-dependent kinase 7 (CDK7) plays a crucial role in regulating the cell cycle and RNA polymerase-based transcription. Overexpression of this kinase is linked with various cancers in humans due to its dual involvement in cell development. Furthermore, emerging evidence has revealed that inhi...

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Detalles Bibliográficos
Autores principales: Kumar, Vikas, Parate, Shraddha, Thakur, Gunjan, Lee, Gihwan, Ro, Hyeon-Su, Kim, Yongseong, Kim, Hong Ja, Kim, Myeong Ok, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468199/
https://www.ncbi.nlm.nih.gov/pubmed/34572383
http://dx.doi.org/10.3390/biomedicines9091197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468199/
https://www.ncbi.nlm.nih.gov/pubmed/34572383
http://dx.doi.org/10.3390/biomedicines9091197

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