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Identification of CDK7 Inhibitors from Natural Sources Using Pharmacoinformatics and Molecular Dynamics Simulations

The cyclin-dependent kinase 7 (CDK7) plays a crucial role in regulating the cell cycle and RNA polymerase-based transcription. Overexpression of this kinase is linked with various cancers in humans due to its dual involvement in cell development. Furthermore, emerging evidence has revealed that inhi...

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Detalles Bibliográficos
Autores principales:	Kumar, Vikas, Parate, Shraddha, Thakur, Gunjan, Lee, Gihwan, Ro, Hyeon-Su, Kim, Yongseong, Kim, Hong Ja, Kim, Myeong Ok, Lee, Keun Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468199/ https://www.ncbi.nlm.nih.gov/pubmed/34572383 http://dx.doi.org/10.3390/biomedicines9091197

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