Cortical Thinning of Motor and Non-Motor Brain Regions Enables Diagnosis of Amyotrophic Lateral Sclerosis and Supports Distinction between Upper- and Lower-Motoneuron Phenotypes

Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder clinically characterized by muscle atrophy and progressive paralysis. In addition to the classical ALS affecting both the upper and lower motoneurons (UMN and LMN), other subtypes with the predominant (or even exclusive)...

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Detalles Bibliográficos
Autores principales: Ferrea, Stefano, Junker, Frederick, Korth, Mira, Gruhn, Kai, Grehl, Torsten, Schmidt-Wilcke, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468309/
https://www.ncbi.nlm.nih.gov/pubmed/34572380
http://dx.doi.org/10.3390/biomedicines9091195

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