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Predominant HLA Alleles and Haplotypes in Mild Adverse Drug Reactions Caused by Allopurinol in Vietnamese Patients with Gout

Allopurinol (ALP) is commonly used as a drug for gout treatment. However, ALP is known to cause cutaneous adverse reactions (CARs) in patients. The HLA-B(*)58:01 allele is considered a biomarker of severe CAR (SCAR) in patients with gout, with symptoms of Stevens Johnson syndrome, and with toxic epi...

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Detalles Bibliográficos
Autores principales: Van Son, Chu, Loan, Nguyen Thi Hong, Trang, Tran Huyen, Thinh, Le Xuan, Khanh, Nguyen Ba, Nhung, Le Thi Hong, Van Hung, Nguyen, Que, Tran Ngoc, Van Lieu, Nguyen, Tung, Pham Dinh, Van Anh, Nguyen Thi, Thang, Nguyen Dinh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468422/
https://www.ncbi.nlm.nih.gov/pubmed/34573954
http://dx.doi.org/10.3390/diagnostics11091611

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