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Predominant HLA Alleles and Haplotypes in Mild Adverse Drug Reactions Caused by Allopurinol in Vietnamese Patients with Gout
Allopurinol (ALP) is commonly used as a drug for gout treatment. However, ALP is known to cause cutaneous adverse reactions (CARs) in patients. The HLA-B(*)58:01 allele is considered a biomarker of severe CAR (SCAR) in patients with gout, with symptoms of Stevens Johnson syndrome, and with toxic epi...
Autores principales: | Van Son, Chu, Loan, Nguyen Thi Hong, Trang, Tran Huyen, Thinh, Le Xuan, Khanh, Nguyen Ba, Nhung, Le Thi Hong, Van Hung, Nguyen, Que, Tran Ngoc, Van Lieu, Nguyen, Tung, Pham Dinh, Van Anh, Nguyen Thi, Thang, Nguyen Dinh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468422/ https://www.ncbi.nlm.nih.gov/pubmed/34573954 http://dx.doi.org/10.3390/diagnostics11091611 |
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