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Cerebellar Cortex and Cerebellar White Matter Volume in Normal Cognition, Mild Cognitive Impairment, and Dementia
The cerebellum is commonly viewed as a structure that is primarily responsible for the coordination of voluntary movement, gait, posture, and speech. Recent research has shown evidence that the cerebellum is also responsible for cognition. We analyzed 28 participants divided into three groups (9 wit...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468434/ https://www.ncbi.nlm.nih.gov/pubmed/34573156 http://dx.doi.org/10.3390/brainsci11091134 |
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author | Zdanovskis, Nauris Platkājis, Ardis Kostiks, Andrejs Grigorjeva, Oļesja Karelis, Guntis |
author_facet | Zdanovskis, Nauris Platkājis, Ardis Kostiks, Andrejs Grigorjeva, Oļesja Karelis, Guntis |
author_sort | Zdanovskis, Nauris |
collection | PubMed |
description | The cerebellum is commonly viewed as a structure that is primarily responsible for the coordination of voluntary movement, gait, posture, and speech. Recent research has shown evidence that the cerebellum is also responsible for cognition. We analyzed 28 participants divided into three groups (9 with normal cognition, 9 with mild cognitive impairment, and 10 with moderate/severe cognitive impairment) based on the Montreal Cognitive Assessment. We analyzed the cerebellar cortex and white matter volume and assessed differences between groups. Participants with normal cognition had higher average values in total cerebellar volume, cerebellar white matter volume, and cerebellar cortex volume in both hemispheres, but by performing the Kruskal–Wallis test, we did not find these values to be statistically significant. |
format | Online Article Text |
id | pubmed-8468434 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84684342021-09-27 Cerebellar Cortex and Cerebellar White Matter Volume in Normal Cognition, Mild Cognitive Impairment, and Dementia Zdanovskis, Nauris Platkājis, Ardis Kostiks, Andrejs Grigorjeva, Oļesja Karelis, Guntis Brain Sci Article The cerebellum is commonly viewed as a structure that is primarily responsible for the coordination of voluntary movement, gait, posture, and speech. Recent research has shown evidence that the cerebellum is also responsible for cognition. We analyzed 28 participants divided into three groups (9 with normal cognition, 9 with mild cognitive impairment, and 10 with moderate/severe cognitive impairment) based on the Montreal Cognitive Assessment. We analyzed the cerebellar cortex and white matter volume and assessed differences between groups. Participants with normal cognition had higher average values in total cerebellar volume, cerebellar white matter volume, and cerebellar cortex volume in both hemispheres, but by performing the Kruskal–Wallis test, we did not find these values to be statistically significant. MDPI 2021-08-26 /pmc/articles/PMC8468434/ /pubmed/34573156 http://dx.doi.org/10.3390/brainsci11091134 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zdanovskis, Nauris Platkājis, Ardis Kostiks, Andrejs Grigorjeva, Oļesja Karelis, Guntis Cerebellar Cortex and Cerebellar White Matter Volume in Normal Cognition, Mild Cognitive Impairment, and Dementia |
title | Cerebellar Cortex and Cerebellar White Matter Volume in Normal Cognition, Mild Cognitive Impairment, and Dementia |
title_full | Cerebellar Cortex and Cerebellar White Matter Volume in Normal Cognition, Mild Cognitive Impairment, and Dementia |
title_fullStr | Cerebellar Cortex and Cerebellar White Matter Volume in Normal Cognition, Mild Cognitive Impairment, and Dementia |
title_full_unstemmed | Cerebellar Cortex and Cerebellar White Matter Volume in Normal Cognition, Mild Cognitive Impairment, and Dementia |
title_short | Cerebellar Cortex and Cerebellar White Matter Volume in Normal Cognition, Mild Cognitive Impairment, and Dementia |
title_sort | cerebellar cortex and cerebellar white matter volume in normal cognition, mild cognitive impairment, and dementia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468434/ https://www.ncbi.nlm.nih.gov/pubmed/34573156 http://dx.doi.org/10.3390/brainsci11091134 |
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