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NF-κB-Dependent and -Independent (Moonlighting) IκBα Functions in Differentiation and Cancer
IκBα is considered to play an almost exclusive role as inhibitor of the NF-κB signaling pathway. However, previous results have demonstrated that SUMOylation imposes a distinct subcellular distribution, regulation, NF-κB-binding affinity and function to the IκBα protein. In this review we discuss th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468488/ https://www.ncbi.nlm.nih.gov/pubmed/34572464 http://dx.doi.org/10.3390/biomedicines9091278 |