Cargando…

Serum Perilipin 2 (PLIN2) Predicts Multiple Organ Dysfunction in Critically Ill Patients

Perilipin 2 (PLIN2) is a lipid droplet protein with various metabolic functions. However, studies investigating PLIN2 in the context of inflammation, especially in systemic and acute inflammation, are lacking. Hence, we assessed the relevance of serum PLIN2 in critically ill patients. We measured se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kurt, Berkan, Buendgens, Lukas, Wirtz, Theresa H., Loosen, Sven H., Schulze-Hagen, Maximilian, Truhn, Daniel, Brozat, Jonathan F., Abu Jhaisha, Samira, Hohlstein, Philipp, Koek, Ger, Weiskirchen, Ralf, Trautwein, Christian, Tacke, Frank, Hamesch, Karim, Koch, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468514/ https://www.ncbi.nlm.nih.gov/pubmed/34572396 http://dx.doi.org/10.3390/biomedicines9091210

Ejemplares similares

Low Myostatin Serum Levels Are Associated with Poor Outcome in Critically Ill Patients
por: Wirtz, Theresa H., et al.
Publicado: (2020)

Clusterin Plasma Concentrations Are Decreased in Sepsis and Inversely Correlated with Established Markers of Inflammation
por: Yagmur, Eray, et al.
Publicado: (2022)

Association of Serum Calprotectin Concentrations with Mortality in Critically Ill and Septic Patients
por: Wirtz, Theresa H., et al.
Publicado: (2020)

Low Serum Levels of Soluble Receptor Activator of Nuclear Factor κ B Ligand (sRANKL) Are Associated with Metabolic Dysregulation and Predict Long-Term Mortality in Critically Ill Patients
por: Puengel, Tobias, et al.
Publicado: (2021)

Secreted Frizzled Related Protein 5 (SFRP5) Serum Levels Are Decreased in Critical Illness and Sepsis and Are Associated with Short-Term Mortality
por: Hohlstein, Philipp, et al.
Publicado: (2023)

Intensivmedizinische Versorgung von Patienten mit akuter Intoxikation in Deutschland – ein Rückblick über 20 Jahre: Akute Vergiftungen auf der Intensivstation
por: Bremen, Kristin, et al.
Publicado: (2022)

CT-based determination of excessive visceral adipose tissue is associated with an impaired survival in critically ill patients
por: Wirtz, Theresa H., et al.
Publicado: (2021)

Decreased Bone Mineral Density Is a Predictor of Poor Survival in Critically Ill Patients
por: Schulze-Hagen, Maximilian F., et al.
Publicado: (2021)

An old foe on peculiar paths: severe falciparum malaria in a Syrian refugee, possibly infected during migrant smuggling from Türkiye to Germany
por: Brozat, Jonathan F., et al.
Publicado: (2023)

Midregional Proadrenomedullin (MRproADM) Serum Levels in Critically Ill Patients Are Associated with Short-Term and Overall Mortality during a Two-Year Follow-Up
por: Buendgens, Lukas, et al.
Publicado: (2020)

Visfatin Serum Levels Predict Mortality in Critically Ill Patients
por: Koch, Alexander, et al.
Publicado: (2018)

Perilipin 2 (PLIN2)-Deficiency Does Not Increase Cholesterol-Induced Toxicity in Macrophages
por: Son, Se-Hee, et al.
Publicado: (2012)

Elevated CTRP1 Plasma Concentration Is Associated with Sepsis and Pre-Existing Type 2 Diabetes Mellitus in Critically Ill Patients
por: Yagmur, Eray, et al.
Publicado: (2019)

High Circulating Caspase-Cleaved Keratin 18 Fragments (M30) Indicate Short-Term Mortality in Critically Ill Patients
por: Koch, Alexander, et al.
Publicado: (2018)

Decreased CTRP3 Plasma Concentrations Are Associated with Sepsis and Predict Mortality in Critically Ill Patients
por: Yagmur, Eray, et al.
Publicado: (2019)

Elevated MR-proANP plasma concentrations are associated with sepsis and predict mortality in critically ill patients
por: Yagmur, Eray, et al.
Publicado: (2019)

Challenges in Pharmacological Intervention in Perilipins (PLINs) to Modulate Lipid Droplet Dynamics in Obesity and Cancer
por: Bombarda-Rocha, Victória, et al.
Publicado: (2023)

Prognostic Relevance of Altered Lymphocyte Subpopulations in Critical Illness and Sepsis
por: Hohlstein, Philipp, et al.
Publicado: (2019)

Neutrophils are a main source of circulating suPAR predicting outcome in critical illness
por: Gussen, Hendrik, et al.
Publicado: (2019)

Correction to: Neutrophils are a main source of circulating suPAR predicting outcome in critical illness
por: Gussen, Hendrik, et al.
Publicado: (2019)

Erratum: Hohlstein, P. et al. Prognostic Relevance of Altered Lymphocyte Subpopulations in Critical Illness and Sepsis. Journal of Clinical Medicine 2019, 8, 353
por: Hohlstein, Philipp, et al.
Publicado: (2019)

Perilipin 5 and Lipocalin 2 Expression in Hepatocellular Carcinoma
por: Asimakopoulou, Anastasia, et al.
Publicado: (2019)

Regulation and Prognostic Relevance of Symmetric Dimethylarginine Serum Concentrations in Critical Illness and Sepsis
por: Koch, Alexander, et al.
Publicado: (2013)

Sphingomyelin phosphodiesterase acid like 3B (SMPDL3b) regulates Perilipin5 (PLIN5) expression and mediates lipid droplet formation
por: Mallela, Shamroop Kumar, et al.
Publicado: (2022)

Imaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish
por: Wilson, Meredith H, et al.
Publicado: (2021)

Sarcopenia Is a Negative Prognostic Factor in Patients Undergoing Transarterial Chemoembolization (TACE) for Hepatic Malignancies
por: Loosen, Sven H., et al.
Publicado: (2019)

Correction: Imaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish
por: Wilson, Meredith H, et al.
Publicado: (2023)

Differential Gene Expression in Circulating CD14(+) Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis
por: Liepelt, Anke, et al.
Publicado: (2020)

Perilipin 5 Ameliorates Hepatic Stellate Cell Activation via SMAD2/3 and SNAIL Signaling Pathways and Suppresses STAT3 Activation
por: Cierpka, Rafael, et al.
Publicado: (2021)

Skeletal Muscle Composition Predicts Outcome in Critically Ill Patients
por: Loosen, Sven H., et al.
Publicado: (2020)

Growth Differentiation Factor-15 Is a Predictor of Mortality in Critically Ill Patients with Sepsis
por: Buendgens, Lukas, et al.
Publicado: (2017)

C-terminal proendothelin-1 (CT-proET-1) is associated with organ failure and predicts mortality in critically ill patients
por: Buendgens, Lukas, et al.
Publicado: (2017)

Plin5/p-Plin5 Guards Diabetic CMECs by Regulating FFAs Metabolism Bidirectionally
por: Du, Jin, et al.
Publicado: (2019)

Elevated circulating soluble interleukin-2 receptor in patients with chronic liver diseases is associated with non-classical monocytes
por: Seidler, Sebastian, et al.
Publicado: (2012)

Relevance of Serum Leptin and Leptin-Receptor Concentrations in Critically Ill Patients
por: Koch, Alexander, et al.
Publicado: (2010)

PLIN1 Haploinsufficiency Is Not Associated With Lipodystrophy
por: Laver, Thomas W, et al.
Publicado: (2018)

Macrophage migration inhibitory factor predicts an unfavorable outcome after transarterial chemoembolization for hepatic malignancies
por: Wirtz, Theresa H., et al.
Publicado: (2021)

IL-6 and IL-8 Serum Levels Predict Tumor Response and Overall Survival after TACE for Primary and Secondary Hepatic Malignancies
por: Loosen, Sven H., et al.
Publicado: (2018)

Skeletal muscle PLIN3 and PLIN5 are serine phosphorylated at rest and following lipolysis during adrenergic or contractile stimulation
por: MacPherson, Rebecca E K, et al.
Publicado: (2013)

A Radiomics Approach to Predict the Emergence of New Hepatocellular Carcinoma in Computed Tomography for High-Risk Patients with Liver Cirrhosis
por: Tietz, Eric, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f2r30n2buaol2vepm1us64vnl1