Cargando…

WNT/β-Catenin Signaling Promotes TGF-β-Mediated Activation of Human Cardiac Fibroblasts by Enhancing IL-11 Production

Cardiac fibrosis is a pathological process associated with the development of heart failure. TGF-β and WNT signaling have been implicated in pathogenesis of cardiac fibrosis, however, little is known about molecular cross-talk between these two pathways. The aim of this study was to examine the effe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Działo, Edyta, Czepiel, Marcin, Tkacz, Karolina, Siedlar, Maciej, Kania, Gabriela, Błyszczuk, Przemysław
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468519/ https://www.ncbi.nlm.nih.gov/pubmed/34576234 http://dx.doi.org/10.3390/ijms221810072

Ejemplares similares

WNT3a and WNT5a Transported by Exosomes Activate WNT Signaling Pathways in Human Cardiac Fibroblasts
por: Działo, Edyta, et al.
Publicado: (2019)

Angiotensin II receptor 1 controls profibrotic Wnt/β-catenin signalling in experimental autoimmune myocarditis
por: Czepiel, Marcin, et al.
Publicado: (2021)

Haploinsufficient Rock1(+/−) and Rock2(+/−) Mice Are Not Protected from Cardiac Inflammation and Postinflammatory Fibrosis in Experimental Autoimmune Myocarditis
por: Tkacz, Karolina, et al.
Publicado: (2020)

T Lymphocyte-Derived Exosomes Transport MEK1/2 and ERK1/2 and Induce NOX4-Dependent Oxidative Stress in Cardiac Microvascular Endothelial Cells
por: Rolski, Filip, et al.
Publicado: (2022)

Identification and Isolation of Cardiac Fibroblasts From the Adult Mouse Heart Using Two-Color Flow Cytometry
por: Stellato, Mara, et al.
Publicado: (2019)

Activation of WNT / β-Catenin Signaling in Pulmonary Fibroblasts by TGF-β(1) Is Increased in Chronic Obstructive Pulmonary Disease
por: Baarsma, Hoeke A., et al.
Publicado: (2011)

Activated Cardiac Fibroblasts Control Contraction of Human Fibrotic Cardiac Microtissues by a β-Adrenoreceptor-Dependent Mechanism
por: Błyszczuk, Przemysław, et al.
Publicado: (2020)

Loss of TGF-β or Wnt5a results in an increase in Wnt/β-catenin activity and redirects mammary tumour phenotype
por: Roarty, Kevin, et al.
Publicado: (2009)

TGF-β Prevents Phosphate-Induced Osteogenesis through Inhibition of BMP and Wnt/β-Catenin Pathways
por: Guerrero, Fátima, et al.
Publicado: (2014)

TGF‐β/Smad and Wnt/β‐catenin signaling pathways are involved in renal fibrosis and its therapies
por: Ying, Jialiang, et al.
Publicado: (2020)

Correction: TGF-β Prevents Phosphate-Induced Osteogenesis through Inhibition of BMP and Wnt/β-Catenin Pathways
Publicado: (2014)

Aptamers and Their Potential to Selectively Target Aspects of EGF, Wnt/β-Catenin and TGFβ–Smad Family Signaling
por: Conidi, Andrea, et al.
Publicado: (2013)

TGF-β1 enhanced myocardial differentiation through inhibition of the Wnt/β-catenin pathway with rat BMSCs
por: Lv, Yang, et al.
Publicado: (2020)

Hierarchy of TGFβ/SMAD, Hippo/YAP/TAZ, and Wnt/β-catenin signaling in melanoma phenotype switching
por: Lüönd, Fabiana, et al.
Publicado: (2021)

Sera of patients with axial spondyloarthritis (axSpA) enhance osteoclastogenic potential of monocytes isolated from healthy individuals
por: Korkosz, Mariusz, et al.
Publicado: (2018)

Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling
por: Lin, Chung-Ming, et al.
Publicado: (2017)

Interactions between TGF-β1, canonical WNT/β-catenin pathway and PPAR γ in radiation-induced fibrosis
por: Vallée, Alexandre, et al.
Publicado: (2017)

Activation of Wnt/β‐catenin signalling is required for TGF‐β/Smad2/3 signalling during myofibroblast proliferation
por: Xu, Liang, et al.
Publicado: (2017)

Estrogen attenuates TGF-β1-induced EMT in intrauterine adhesion by activating Wnt/β-catenin signaling pathway
por: Cao, Jia, et al.
Publicado: (2020)

Simvastatin inhibits stem cell proliferation in human leiomyoma via TGF‐β3 and Wnt/β‐Catenin pathways
por: Afrin, Sadia, et al.
Publicado: (2022)

Tangshen Formula Improves Diabetes-Associated Myocardial Fibrosis by Inhibiting TGF-β/Smads and Wnt/β-Catenin Pathways
por: Hu, Lin, et al.
Publicado: (2021)

WNKs in Wnt/β-catenin signaling
por: Serysheva, Ekatherina, et al.
Publicado: (2014)

Wnt/β-Catenin Signaling and Obesity
por: Chen, Na, et al.
Publicado: (2018)

Wnt/β-Catenin Signaling Inhibits Osteogenic Differentiation in Human Periodontal Ligament Fibroblasts
por: Iizumi, Ryoya, et al.
Publicado: (2022)

FOXF1 attenuates TGF‑β1‑induced bronchial epithelial cell injury by inhibiting CDH11‑mediated Wnt/β‑catenin signaling
por: Chen, Qin, et al.
Publicado: (2023)

Calcitonin protects rat chondrocytes from IL-1β injury via the Wnt/β-catenin pathway
por: Bai, Mingxiao, et al.
Publicado: (2019)

Feedback Activation of Basic Fibroblast Growth Factor Signaling via the Wnt/β-Catenin Pathway in Skin Fibroblasts
por: Wang, Xu, et al.
Publicado: (2017)

Serum concentration of dickkopf-related protein 1 (DKK1) in psoriatic arthritis in the context of bone remodelling
por: Biedroń, Grzegorz, et al.
Publicado: (2023)

Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth
por: Telerman, Stephanie B., et al.
Publicado: (2017)

TGFβ induced factor homeobox 1 promotes colorectal cancer development through activating Wnt/β-catenin signaling
por: Wang, Ji-Lian, et al.
Publicado: (2017)

COL5A2 Inhibits the TGF-β and Wnt/β-Catenin Signaling Pathways to Inhibit the Invasion and Metastasis of Osteosarcoma
por: Han, Yan-Long, et al.
Publicado: (2022)

Novel β-carbolines inhibit Wnt/β-catenin signaling
por: Kong, L, et al.
Publicado: (2015)

Interaction between Wnt/β-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of β-catenin and RAS by targeting the Wnt/β-catenin pathway
por: Jeong, Woo-Jeong, et al.
Publicado: (2018)

Inhibitors of DNA methylation support TGF-β1-induced IL11 expression in gingival fibroblasts
por: Sufaru, Irina-Georgeta, et al.
Publicado: (2017)

Editorial: Cutting Edge Methodologies in Experimental Cardiovascular Research
por: Błyszczuk, Przemysław, et al.
Publicado: (2020)

IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts
por: Adami, Eleonora, et al.
Publicado: (2021)

The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis
por: Seidenberg, Jemima, et al.
Publicado: (2021)

Wnt/β-catenin signaling in heart regeneration
por: Ozhan, Gunes, et al.
Publicado: (2015)

Wnt/β-catenin signaling and kidney fibrosis
por: Tan, Roderick J, et al.
Publicado: (2014)

Regulation of Wnt/β-catenin signaling by herpesviruses
por: Zwezdaryk, Kevin J, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_duflqfms1uoo0n0rop0tt07eog