Cargando…
The Long-Acting Echinocandin, Rezafungin, Prevents Pneumocystis Pneumonia and Eliminates Pneumocystis from the Lungs in Prophylaxis and Murine Treatment Models
Rezafungin is a novel echinocandin in Phase 3 development for prevention of invasive fungal disease caused by Candida spp., Aspergillus spp. and Pneumocystis jirovecii in blood and marrow transplantation patients. For such patients, standard antifungal prophylaxis currently comprises an azole for Ca...
Autores principales: | Cushion, Melanie T., Ashbaugh, Alan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468546/ https://www.ncbi.nlm.nih.gov/pubmed/34575785 http://dx.doi.org/10.3390/jof7090747 |
Ejemplares similares
-
Efficacy of Rezafungin in Prophylactic Mouse Models of Invasive Candidiasis, Aspergillosis, and Pneumocystis Pneumonia
por: Miesel, Lynn, et al.
Publicado: (2021) -
1251. Prevention of Pneumocystis Pneumonia by Ibrexafungerp in a Murine Prophylaxis Model
por: Borroto-Esoda, Katyna, et al.
Publicado: (2020) -
Echinocandin Treatment of Pneumocystis Pneumonia in Rodent Models Depletes Cysts Leaving Trophic Burdens That Cannot Transmit the Infection
por: Cushion, Melanie T., et al.
Publicado: (2010) -
The Promise of Lung Organoids for Growth and Investigation of Pneumocystis Species
por: Tisdale-Macioce, Nikeya, et al.
Publicado: (2021) -
The Effects of Sex and Strain on Pneumocystis murina Fungal Burdens in Mice
por: Macioce-Tisdale, Nikeya L., et al.
Publicado: (2022)