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α-Lipoic Acid Improves Hepatic Metabolic Dysfunctions in Acute Intermittent Porphyria: A Proof-of-Concept Study

Background: Acute intermittent porphyria (AIP) is caused by the haploinsufficiency of porphobilinogen deaminase (PBGD) enzymatic activity. Acute attacks occur in response to fasting, and alterations in glucose metabolism, insulin resistance, and mitochondrial turnover may be involved in AIP pathophy...

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Detalles Bibliográficos
Autores principales:	Longo, Miriam, Paolini, Erika, Meroni, Marica, Duca, Lorena, Motta, Irene, Fracanzani, Anna Ludovica, Di Pierro, Elena, Dongiovanni, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468570/ https://www.ncbi.nlm.nih.gov/pubmed/34573969 http://dx.doi.org/10.3390/diagnostics11091628

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