Co-Spray Dried Nafamostat Mesylate with Lecithin and Mannitol as Respirable Microparticles for Targeted Pulmonary Delivery: Pharmacokinetics and Lung Distribution in Rats

Coronavirus disease 2019 (COVID-19), caused by a new strain of coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading rapidly worldwide. Nafamostat mesylate (NFM) suppresses transmembrane serine protease 2 and SARS-CoV-2 S protein-mediated fusion. In this study...

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Detalles Bibliográficos
Autores principales: Kang, Ji-Hyun, Kim, Young-Jin, Yang, Min-Seok, Shin, Dae Hwan, Kim, Dong-Wook, Park, Il Yeong, Park, Chun-Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468663/
https://www.ncbi.nlm.nih.gov/pubmed/34575594
http://dx.doi.org/10.3390/pharmaceutics13091519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468663/
https://www.ncbi.nlm.nih.gov/pubmed/34575594
http://dx.doi.org/10.3390/pharmaceutics13091519

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