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Applications of Aptamer-Bound Nanomaterials in Cancer Therapy
Cancer is still a major disease that threatens human life. Although traditional cancer treatment methods are widely used, they still have many disadvantages. Aptamers, owing to their small size, low toxicity, good specificity, and excellent biocompatibility, have been widely applied in biomedical ar...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468797/ https://www.ncbi.nlm.nih.gov/pubmed/34562934 http://dx.doi.org/10.3390/bios11090344 |
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author | Zhu, Liangxi Zhao, Jingzhou Guo, Zhukang Liu, Yuan Chen, Hui Chen, Zhu He, Nongyue |
author_facet | Zhu, Liangxi Zhao, Jingzhou Guo, Zhukang Liu, Yuan Chen, Hui Chen, Zhu He, Nongyue |
author_sort | Zhu, Liangxi |
collection | PubMed |
description | Cancer is still a major disease that threatens human life. Although traditional cancer treatment methods are widely used, they still have many disadvantages. Aptamers, owing to their small size, low toxicity, good specificity, and excellent biocompatibility, have been widely applied in biomedical areas. Therefore, the combination of nanomaterials with aptamers offers a new method for cancer treatment. First, we briefly introduce the situation of cancer treatment and aptamers. Then, we discuss the application of aptamers in breast cancer treatment, lung cancer treatment, and other cancer treatment methods. Finally, perspectives on challenges and future applications of aptamers in cancer therapy are discussed. |
format | Online Article Text |
id | pubmed-8468797 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84687972021-09-27 Applications of Aptamer-Bound Nanomaterials in Cancer Therapy Zhu, Liangxi Zhao, Jingzhou Guo, Zhukang Liu, Yuan Chen, Hui Chen, Zhu He, Nongyue Biosensors (Basel) Review Cancer is still a major disease that threatens human life. Although traditional cancer treatment methods are widely used, they still have many disadvantages. Aptamers, owing to their small size, low toxicity, good specificity, and excellent biocompatibility, have been widely applied in biomedical areas. Therefore, the combination of nanomaterials with aptamers offers a new method for cancer treatment. First, we briefly introduce the situation of cancer treatment and aptamers. Then, we discuss the application of aptamers in breast cancer treatment, lung cancer treatment, and other cancer treatment methods. Finally, perspectives on challenges and future applications of aptamers in cancer therapy are discussed. MDPI 2021-09-18 /pmc/articles/PMC8468797/ /pubmed/34562934 http://dx.doi.org/10.3390/bios11090344 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Zhu, Liangxi Zhao, Jingzhou Guo, Zhukang Liu, Yuan Chen, Hui Chen, Zhu He, Nongyue Applications of Aptamer-Bound Nanomaterials in Cancer Therapy |
title | Applications of Aptamer-Bound Nanomaterials in Cancer Therapy |
title_full | Applications of Aptamer-Bound Nanomaterials in Cancer Therapy |
title_fullStr | Applications of Aptamer-Bound Nanomaterials in Cancer Therapy |
title_full_unstemmed | Applications of Aptamer-Bound Nanomaterials in Cancer Therapy |
title_short | Applications of Aptamer-Bound Nanomaterials in Cancer Therapy |
title_sort | applications of aptamer-bound nanomaterials in cancer therapy |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468797/ https://www.ncbi.nlm.nih.gov/pubmed/34562934 http://dx.doi.org/10.3390/bios11090344 |
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