Cargando…

Limited Impact of Pivalate-Induced Secondary Carnitine Deficiency on Hepatic Transcriptome and Hepatic and Plasma Metabolome in Nursery Pigs

Administration of pivalate has been demonstrated to be suitable for the induction of secondary carnitine deficiency (CD) in pigs, as model objects for humans. In order to comprehensively characterize the metabolic effects of secondary CD in the liver of pigs, the present study aimed to carry out com...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ringseis, Robert, Grundmann, Sarah M., Schuchardt, Sven, Most, Erika, Eder, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468870/ https://www.ncbi.nlm.nih.gov/pubmed/34564388 http://dx.doi.org/10.3390/metabo11090573

Ejemplares similares

Effect of Hermetia illucens Fat, Compared with That of Soybean Oil and Palm Oil, on Hepatic Lipid Metabolism and Plasma Metabolome in Healthy Rats
por: Ringseis, Robert, et al.
Publicado: (2023)

The carnitine status does not affect the contractile and metabolic phenotype of skeletal muscle in pigs
por: Kaup, Daniel, et al.
Publicado: (2018)

Pharmacological doses of niacin stimulate the expression of genes involved in carnitine uptake and biosynthesis and improve the carnitine status of obese Zucker rats
por: Couturier, Aline, et al.
Publicado: (2014)

Genes involved in carnitine synthesis and carnitine uptake are up-regulated in the liver of sows during lactation
por: Rosenbaum, Susann, et al.
Publicado: (2013)

Effect of L-carnitine on the hepatic transcript profile in piglets as animal model
por: Keller, Janine, et al.
Publicado: (2011)

Feeding of Hermetia illucens Larvae Meal Attenuates Hepatic Lipid Synthesis and Fatty Liver Development in Obese Zucker Rats
por: Marschall, Magdalena J. M., et al.
Publicado: (2023)

Regulation of Genes Involved in Carnitine Homeostasis by PPARα across Different Species (Rat, Mouse, Pig, Cattle, Chicken, and Human)
por: Ringseis, Robert, et al.
Publicado: (2012)

Effect of Ecdysterone on the Hepatic Transcriptome and Lipid Metabolism in Lean and Obese Zucker Rats
por: Marschall, Magdalena J. M., et al.
Publicado: (2021)

Carnitine supplementation to obese Zucker rats prevents obesity-induced type II to type I muscle fiber transition and favors an oxidative phenotype of skeletal muscle
por: Couturier, Aline, et al.
Publicado: (2013)

Correction: Carnitine supplementation to obese Zucker rats prevents obesity-induced type I to type II muscle fiber transition and favors an oxidative phenotype of skeletal muscle
por: Couturier, Aline, et al.
Publicado: (2014)

Low availability of carnitine precursors as a possible reason for the diminished plasma carnitine concentrations in pregnant women
por: Ringseis, Robert, et al.
Publicado: (2010)

Two-step Synthesis of Solasodine Pivalate from Diosgenin Pivalate
por: Wojtkielewicz, Agnieszka, et al.
Publicado: (2019)

Dietary moderately oxidized oil activates the Nrf2 signaling pathway in the liver of pigs
por: Varady, Juliane, et al.
Publicado: (2012)

Carnitine transporter OCTN2 and carnitine uptake in bovine kidney cells is regulated by peroxisome proliferator-activated receptor β/δ
por: Zhou, Xiaodan, et al.
Publicado: (2014)

Expression of genes involved in hepatic carnitine synthesis and uptake in dairy cows in the transition period and at different stages of lactation
por: Schlegel, Gloria, et al.
Publicado: (2012)

Comprehensive evaluation of the metabolic effects of insect meal from Tenebrio molitor L. in growing pigs by transcriptomics, metabolomics and lipidomics
por: Meyer, Sandra, et al.
Publicado: (2020)

Performance and Metabolic, Inflammatory, and Oxidative Stress-Related Parameters in Early Lactating Dairy Cows with High and Low Hepatic FGF21 Expression
por: Gessner, Denise K., et al.
Publicado: (2022)

Niacin supplementation increases the number of oxidative type I fibers in skeletal muscle of growing pigs
por: Khan, Muckta, et al.
Publicado: (2013)

Supplemental carnitine affects the microRNA expression profile in skeletal muscle of obese Zucker rats
por: Keller, Janine, et al.
Publicado: (2014)

Effect of replacement of soybean oil by Hermetia illucens fat on performance, digestibility, cecal microbiome, liver transcriptome and liver and plasma lipidomes of broilers
por: Schäfer, Lea, et al.
Publicado: (2023)

A High-Phosphorus Diet Moderately Alters the Lipidome and Transcriptome in the Skeletal Muscle of Adult Mice
por: Grundmann, Sarah M., et al.
Publicado: (2023)

Tenebrio molitor Larvae Meal Affects the Cecal Microbiota of Growing Pigs
por: Meyer, Sandra, et al.
Publicado: (2020)

Supplementation of a grape seed and grape marc meal extract decreases activities of the oxidative stress-responsive transcription factors NF-κB and Nrf2 in the duodenal mucosa of pigs
por: Gessner, Denise K, et al.
Publicado: (2013)

Supplementation of Sulfur-Containing Amino Acids or Essential Amino Acids Does Not Reverse the Hepatic Lipid-Lowering Effect of a Protein-Rich Insect Meal in Obese Zucker Rats
por: Meyer, Sandra, et al.
Publicado: (2020)

Carnitine-related hypoglycemia caused by 3 days of pivalate antibiotic therapy in a patient with severe muscular dystrophy: a case report
por: Ito, Masanori, et al.
Publicado: (2017)

Niacin in Pharmacological Doses Alters MicroRNA Expression in Skeletal Muscle of Obese Zucker Rats
por: Couturier, Aline, et al.
Publicado: (2014)

Crystal structures of two polymorphs of tixocortol pivalate
por: Rousselin, Yoann, et al.
Publicado: (2021)

Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes
por: Cheng, Xinyi, et al.
Publicado: (2021)

Heat stress in pigs and broilers: role of gut dysbiosis in the impairment of the gut-liver axis and restoration of these effects by probiotics, prebiotics and synbiotics
por: Ringseis, Robert, et al.
Publicado: (2022)

Dietary moderately oxidized oil induces expression of fibroblast growth factor 21 in the liver of pigs
por: Varady, Juliane, et al.
Publicado: (2012)

Supplementation of carnitine leads to an activation of the IGF-1/PI3K/Akt signalling pathway and down regulates the E3 ligase MuRF1 in skeletal muscle of rats
por: Keller, Janine, et al.
Publicado: (2013)

Outbreak of Hepatitis A in a Nursery School
por: Galmes-Truyols, Antonia, et al.
Publicado: (2013)

Enantiospecific, Nickel-Catalyzed Cross-Couplings of Allylic Pivalates and Arylboroxines
por: Srinivas, Harathi D., et al.
Publicado: (2014)

Use of Deoxycorticosterone Pivalate by Veterinarians: A Western European Survey
por: Rebocho, Rita, et al.
Publicado: (2021)

Effect of supplementing lactation and nursery pig diets with capsaicin on growth performance and gene expression of nursery pigs
por: Rosa-Medina, Eduardo A, et al.
Publicado: (2021)

Organic selenium supplement partially alleviated diquat-induced oxidative insults and hepatic metabolic stress in nursery pigs
por: Doan, Nicole, et al.
Publicado: (2020)

Carnitine Orotate Complex Ameliorates Insulin Resistance and Hepatic Steatosis Through Carnitine Acetyltransferase Pathway
por: Hong, Jung-Hee, et al.
Publicado: (2021)

Secondary Carnitine Deficiency in Environmental Enteric Dysfunction
por: Ramakrishnan, Girija, et al.
Publicado: (2017)

Desoxycorticosterone Pivalate Duration of Action and Individualized Dosing Intervals in Dogs with Primary Hypoadrenocorticism
por: Jaffey, J.A., et al.
Publicado: (2017)

Cobalt-catalyzed acylation-reactions of (hetero)arylzinc pivalates with thiopyridyl ester derivatives
por: Lutter, Ferdinand H., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_jp64opa924ip95d361dc23f9qt