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Foodborne Botulism in Western Romania: Ten Years’ Experience at a Tertiary Infectious Disease Hospital

Objectives: The purpose of this study was to analyze epidemiological data concerning foodborne botulism in Western Romania over the last decade. Botulism, the toxin formed by the bacterium Clostridium botulinum, results in a neuroparalytic disorder capable of severe clinical progression that begins...

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Autores principales: Marincu, Iosif, Bratosin, Felix, Vidican, Iulia, Cerbu, Bianca, Suciu, Oana, Turaiche, Mirela, Tirnea, Livius, Timircan, Madalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469094/
https://www.ncbi.nlm.nih.gov/pubmed/34574922
http://dx.doi.org/10.3390/healthcare9091149
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author Marincu, Iosif
Bratosin, Felix
Vidican, Iulia
Cerbu, Bianca
Suciu, Oana
Turaiche, Mirela
Tirnea, Livius
Timircan, Madalina
author_facet Marincu, Iosif
Bratosin, Felix
Vidican, Iulia
Cerbu, Bianca
Suciu, Oana
Turaiche, Mirela
Tirnea, Livius
Timircan, Madalina
author_sort Marincu, Iosif
collection PubMed
description Objectives: The purpose of this study was to analyze epidemiological data concerning foodborne botulism in Western Romania over the last decade. Botulism, the toxin formed by the bacterium Clostridium botulinum, results in a neuroparalytic disorder capable of severe clinical progression that begins in the cranial nerves and progressively descends. Preventing progression to a severe case entails timely diagnosis since curative assets are restricted. Ingesting food containing a preformed toxin (foodborne botulism) is the most typical form. Methods: Medical records were retrospectively analyzed from 2010 to 2020 for all food botulism cases. A seroneutralization test was performed with type A, B and E anti-botulinum sera to establish the kind of toxin involved. Results: Overall, 18 cases of foodborne botulism were admitted to the hospital during this period and confirmed by laboratory analysis. Most of the participants in our study were men (61.1%), and 77.8% of the total lived in rural areas. All the participants showed classic symptoms of botulism, and dysphagia was present in all cases. The trivalent ABE antitoxin was administered by the hospital, and toxin type B was isolated in all patients. The main sources of the toxin were pork, ham and canned pork meat. Conclusions: Stronger efforts are needed to foster community awareness of foodborne botulism, particularly in home-preserved food.
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spelling pubmed-84690942021-09-27 Foodborne Botulism in Western Romania: Ten Years’ Experience at a Tertiary Infectious Disease Hospital Marincu, Iosif Bratosin, Felix Vidican, Iulia Cerbu, Bianca Suciu, Oana Turaiche, Mirela Tirnea, Livius Timircan, Madalina Healthcare (Basel) Article Objectives: The purpose of this study was to analyze epidemiological data concerning foodborne botulism in Western Romania over the last decade. Botulism, the toxin formed by the bacterium Clostridium botulinum, results in a neuroparalytic disorder capable of severe clinical progression that begins in the cranial nerves and progressively descends. Preventing progression to a severe case entails timely diagnosis since curative assets are restricted. Ingesting food containing a preformed toxin (foodborne botulism) is the most typical form. Methods: Medical records were retrospectively analyzed from 2010 to 2020 for all food botulism cases. A seroneutralization test was performed with type A, B and E anti-botulinum sera to establish the kind of toxin involved. Results: Overall, 18 cases of foodborne botulism were admitted to the hospital during this period and confirmed by laboratory analysis. Most of the participants in our study were men (61.1%), and 77.8% of the total lived in rural areas. All the participants showed classic symptoms of botulism, and dysphagia was present in all cases. The trivalent ABE antitoxin was administered by the hospital, and toxin type B was isolated in all patients. The main sources of the toxin were pork, ham and canned pork meat. Conclusions: Stronger efforts are needed to foster community awareness of foodborne botulism, particularly in home-preserved food. MDPI 2021-09-02 /pmc/articles/PMC8469094/ /pubmed/34574922 http://dx.doi.org/10.3390/healthcare9091149 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Marincu, Iosif
Bratosin, Felix
Vidican, Iulia
Cerbu, Bianca
Suciu, Oana
Turaiche, Mirela
Tirnea, Livius
Timircan, Madalina
Foodborne Botulism in Western Romania: Ten Years’ Experience at a Tertiary Infectious Disease Hospital
title Foodborne Botulism in Western Romania: Ten Years’ Experience at a Tertiary Infectious Disease Hospital
title_full Foodborne Botulism in Western Romania: Ten Years’ Experience at a Tertiary Infectious Disease Hospital
title_fullStr Foodborne Botulism in Western Romania: Ten Years’ Experience at a Tertiary Infectious Disease Hospital
title_full_unstemmed Foodborne Botulism in Western Romania: Ten Years’ Experience at a Tertiary Infectious Disease Hospital
title_short Foodborne Botulism in Western Romania: Ten Years’ Experience at a Tertiary Infectious Disease Hospital
title_sort foodborne botulism in western romania: ten years’ experience at a tertiary infectious disease hospital
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469094/
https://www.ncbi.nlm.nih.gov/pubmed/34574922
http://dx.doi.org/10.3390/healthcare9091149
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