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3D Dosimetry Based on LiMgPO(4) OSL Silicone Foils: Facilitating the Verification of Eye-Ball Cancer Proton Radiotherapy

A direct verification of the three-dimensional (3D) proton clinical treatment plan prepared for tumor in the eyeball, using the Eclipse Ocular Proton Planning system (by Varian Medical Systems), has been presented. To achieve this, a prototype of the innovative two-dimensional (2D) circular silicone...

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Autores principales: Sądel, Michał, Gajewski, Jan, Sowa, Urszula, Swakoń, Jan, Kajdrowicz, Tomasz, Bilski, Paweł, Kłosowski, Mariusz, Pędracka, Anna, Horwacik, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469107/
https://www.ncbi.nlm.nih.gov/pubmed/34577220
http://dx.doi.org/10.3390/s21186015
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author Sądel, Michał
Gajewski, Jan
Sowa, Urszula
Swakoń, Jan
Kajdrowicz, Tomasz
Bilski, Paweł
Kłosowski, Mariusz
Pędracka, Anna
Horwacik, Tomasz
author_facet Sądel, Michał
Gajewski, Jan
Sowa, Urszula
Swakoń, Jan
Kajdrowicz, Tomasz
Bilski, Paweł
Kłosowski, Mariusz
Pędracka, Anna
Horwacik, Tomasz
author_sort Sądel, Michał
collection PubMed
description A direct verification of the three-dimensional (3D) proton clinical treatment plan prepared for tumor in the eyeball, using the Eclipse Ocular Proton Planning system (by Varian Medical Systems), has been presented. To achieve this, a prototype of the innovative two-dimensional (2D) circular silicone foils, made of a polymer with the embedded optically stimulated luminescence (OSL) material in powder form (LiMgPO(4)), and a self-developed optical imaging system, consisting of an illuminating light source and a high-sensitive CCD camera has been applied. A specially designed lifelike eyeball phantom has been used, constructed from 40 flat sheet LMP-based silicone foils stacked and placed together behind a spherical phantom made by polystyrene, all to reflect the curvature of the real eyeball. Two-dimensional OSL signals were captured and further analyzed from each single silicone foil after irradiation using a dedicated patient collimator and a 58.8 MeV modulated proton beam. The reconstructed 3D proton depth dose distribution matches very well with the clinical treatment plan, allowing for the consideration of the new OSL system for further 3D dosimetry applications within the proton radiotherapy area.
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spelling pubmed-84691072021-09-27 3D Dosimetry Based on LiMgPO(4) OSL Silicone Foils: Facilitating the Verification of Eye-Ball Cancer Proton Radiotherapy Sądel, Michał Gajewski, Jan Sowa, Urszula Swakoń, Jan Kajdrowicz, Tomasz Bilski, Paweł Kłosowski, Mariusz Pędracka, Anna Horwacik, Tomasz Sensors (Basel) Article A direct verification of the three-dimensional (3D) proton clinical treatment plan prepared for tumor in the eyeball, using the Eclipse Ocular Proton Planning system (by Varian Medical Systems), has been presented. To achieve this, a prototype of the innovative two-dimensional (2D) circular silicone foils, made of a polymer with the embedded optically stimulated luminescence (OSL) material in powder form (LiMgPO(4)), and a self-developed optical imaging system, consisting of an illuminating light source and a high-sensitive CCD camera has been applied. A specially designed lifelike eyeball phantom has been used, constructed from 40 flat sheet LMP-based silicone foils stacked and placed together behind a spherical phantom made by polystyrene, all to reflect the curvature of the real eyeball. Two-dimensional OSL signals were captured and further analyzed from each single silicone foil after irradiation using a dedicated patient collimator and a 58.8 MeV modulated proton beam. The reconstructed 3D proton depth dose distribution matches very well with the clinical treatment plan, allowing for the consideration of the new OSL system for further 3D dosimetry applications within the proton radiotherapy area. MDPI 2021-09-08 /pmc/articles/PMC8469107/ /pubmed/34577220 http://dx.doi.org/10.3390/s21186015 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sądel, Michał
Gajewski, Jan
Sowa, Urszula
Swakoń, Jan
Kajdrowicz, Tomasz
Bilski, Paweł
Kłosowski, Mariusz
Pędracka, Anna
Horwacik, Tomasz
3D Dosimetry Based on LiMgPO(4) OSL Silicone Foils: Facilitating the Verification of Eye-Ball Cancer Proton Radiotherapy
title 3D Dosimetry Based on LiMgPO(4) OSL Silicone Foils: Facilitating the Verification of Eye-Ball Cancer Proton Radiotherapy
title_full 3D Dosimetry Based on LiMgPO(4) OSL Silicone Foils: Facilitating the Verification of Eye-Ball Cancer Proton Radiotherapy
title_fullStr 3D Dosimetry Based on LiMgPO(4) OSL Silicone Foils: Facilitating the Verification of Eye-Ball Cancer Proton Radiotherapy
title_full_unstemmed 3D Dosimetry Based on LiMgPO(4) OSL Silicone Foils: Facilitating the Verification of Eye-Ball Cancer Proton Radiotherapy
title_short 3D Dosimetry Based on LiMgPO(4) OSL Silicone Foils: Facilitating the Verification of Eye-Ball Cancer Proton Radiotherapy
title_sort 3d dosimetry based on limgpo(4) osl silicone foils: facilitating the verification of eye-ball cancer proton radiotherapy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469107/
https://www.ncbi.nlm.nih.gov/pubmed/34577220
http://dx.doi.org/10.3390/s21186015
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