MicroRNAs in Hypertrophic, Arrhythmogenic and Dilated Cardiomyopathy

MicroRNAs (miRNAs) are a class of non-coding RNAs of about 20 nucleotides in length, involved in the regulation of many biochemical pathways in the human body. The level of miRNAs in tissues and circulation can be deregulated because of altered pathophysiological mechanisms; thus, they can be employ...

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Autores principales: Chiti, Enrica, Di Paolo, Marco, Turillazzi, Emanuela, Rocchi, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469137/
https://www.ncbi.nlm.nih.gov/pubmed/34574061
http://dx.doi.org/10.3390/diagnostics11091720
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author Chiti, Enrica
Di Paolo, Marco
Turillazzi, Emanuela
Rocchi, Anna
author_facet Chiti, Enrica
Di Paolo, Marco
Turillazzi, Emanuela
Rocchi, Anna
author_sort Chiti, Enrica
collection PubMed
description MicroRNAs (miRNAs) are a class of non-coding RNAs of about 20 nucleotides in length, involved in the regulation of many biochemical pathways in the human body. The level of miRNAs in tissues and circulation can be deregulated because of altered pathophysiological mechanisms; thus, they can be employed as biomarkers for different pathological conditions, such as cardiac diseases. This review summarizes published findings of these molecular biomarkers in the three most common structural cardiomyopathies: human dilated, arrhythmogenic and hypertrophic cardiomyopathy.
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spelling pubmed-84691372021-09-27 MicroRNAs in Hypertrophic, Arrhythmogenic and Dilated Cardiomyopathy Chiti, Enrica Di Paolo, Marco Turillazzi, Emanuela Rocchi, Anna Diagnostics (Basel) Review MicroRNAs (miRNAs) are a class of non-coding RNAs of about 20 nucleotides in length, involved in the regulation of many biochemical pathways in the human body. The level of miRNAs in tissues and circulation can be deregulated because of altered pathophysiological mechanisms; thus, they can be employed as biomarkers for different pathological conditions, such as cardiac diseases. This review summarizes published findings of these molecular biomarkers in the three most common structural cardiomyopathies: human dilated, arrhythmogenic and hypertrophic cardiomyopathy. MDPI 2021-09-19 /pmc/articles/PMC8469137/ /pubmed/34574061 http://dx.doi.org/10.3390/diagnostics11091720 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chiti, Enrica
Di Paolo, Marco
Turillazzi, Emanuela
Rocchi, Anna
MicroRNAs in Hypertrophic, Arrhythmogenic and Dilated Cardiomyopathy
title MicroRNAs in Hypertrophic, Arrhythmogenic and Dilated Cardiomyopathy
title_full MicroRNAs in Hypertrophic, Arrhythmogenic and Dilated Cardiomyopathy
title_fullStr MicroRNAs in Hypertrophic, Arrhythmogenic and Dilated Cardiomyopathy
title_full_unstemmed MicroRNAs in Hypertrophic, Arrhythmogenic and Dilated Cardiomyopathy
title_short MicroRNAs in Hypertrophic, Arrhythmogenic and Dilated Cardiomyopathy
title_sort micrornas in hypertrophic, arrhythmogenic and dilated cardiomyopathy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469137/
https://www.ncbi.nlm.nih.gov/pubmed/34574061
http://dx.doi.org/10.3390/diagnostics11091720
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