Cargando…

Convenient Synthesis of Pyrazolo[4′,3′:5,6]pyrano[4,3-c][1,2]oxazoles via Intramolecular Nitrile Oxide Cycloaddition

A simple and efficient synthetic route to the novel 3a,4-dihydro-3H,7H- and 4H,7H-pyrazolo[4′,3′:5,6]pyrano[4,3-c][1,2]oxazole ring systems from 3-(prop-2-en-1-yloxy)- or 3-(prop-2-yn-1-yloxy)-1H-pyrazole-4-carbaldehyde oximes has been developed by employing the intramolecular nitrile oxide cycloadd...

Descripción completa

Detalles Bibliográficos
Autores principales:	Milišiūnaitė, Vaida, Plytninkienė, Elena, Bakšienė, Roberta, Bieliauskas, Aurimas, Krikštolaitytė, Sonata, Račkauskienė, Greta, Arbačiauskienė, Eglė, Šačkus, Algirdas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469150/ https://www.ncbi.nlm.nih.gov/pubmed/34577075 http://dx.doi.org/10.3390/molecules26185604

Ejemplares similares

Regioselective synthesis of methyl 5-(N-Boc-cycloaminyl)-1,2-oxazole-4-carboxylates as new amino acid-like building blocks
por: Bruzgulienė, Jolita, et al.
Publicado: (2022)

Synthesis and Characterization of Novel Heterocyclic Chalcones from 1-Phenyl-1H-pyrazol-3-ol
por: Urbonavičius, Arminas, et al.
Publicado: (2022)

Synthesis and Characterization of New Pyrano[2,3-c]pyrazole Derivatives as 3-Hydroxyflavone Analogues
por: Urbonavičius, Arminas, et al.
Publicado: (2023)

Synthesis of New Azetidine and Oxetane Amino Acid Derivatives through Aza-Michael Addition of NH-Heterocycles with Methyl 2-(Azetidin- or Oxetan-3-Ylidene)Acetates
por: Gudelis, Emilis, et al.
Publicado: (2023)

Synthesis and Characterization of Novel Methyl (3)5-(N-Boc-piperidinyl)-1H-pyrazole-4-carboxylates
por: Matulevičiūtė, Gita, et al.
Publicado: (2021)

On the Tautomerism of N-Substituted Pyrazolones: 1,2-Dihydro-3H-pyrazol-3-ones versus 1H-Pyrazol-3-ols
por: Arbačiauskienė, Eglė, et al.
Publicado: (2018)

Convenient Synthesis of N-Heterocycle-Fused Tetrahydro-1,4-diazepinones
por: Dzedulionytė, Karolina, et al.
Publicado: (2022)

Synthesis and Antiproliferative Activity of 2,4,6,7-Tetrasubstituted-2H-pyrazolo[4,3-c]pyridines
por: Razmienė, Beatričė, et al.
Publicado: (2021)

Synthesis of 2H-furo[2,3-c]pyrazole ring systems through silver(I) ion-mediated ring-closure reaction
por: Milišiūnaitė, Vaida, et al.
Publicado: (2019)

Colorimetric Cyanide Chemosensor Based on 1′,3,3′,4-Tetrahydrospiro[chromene-2,2′-indole]
por: Dagilienė, Miglė, et al.
Publicado: (2015)

Facile synthesis of new N-(aminocycloalkylene)amino acid compounds using chiral triflate esters with N-Boc-aminopyrrolidines and N-Boc-aminopiperidines
por: Matulevičiūtė, Gita, et al.
Publicado: (2023)

Dipyrazolo[1,5-a:4',3'-c]pyridines – a new heterocyclic system accessed via multicomponent reaction
por: Holzer, Wolfgang, et al.
Publicado: (2012)

An umpolung strategy for intermolecular [2 + 2 + 1] cycloaddition of aryl aldehydes and nitriles: a facile access to 2,4,5-trisubstituted oxazoles
por: Basavaiah, Deevi, et al.
Publicado: (2022)

Synthesis of trifluoromethyl-substituted pyrazolo[4,3-c]pyridines – sequential versus multicomponent reaction approach
por: Palka, Barbara, et al.
Publicado: (2014)

Polyfunctional Nitriles in Organic Syntheses: A Novel Route to Aminopyrroles, Pyridazines and Pyrazolo[3,4-c]pyridazines
por: Al-Mousawi, Saleh M., et al.
Publicado: (2009)

Gold-catalyzed formal [4π + 2π]-cycloadditions of propiolate derivatives with unactivated nitriles
por: Karad, Somnath Narayan, et al.
Publicado: (2015)

Regioselectivity of 1,3-dipolar cycloadditions and antimicrobial activity of isoxazoline, pyrrolo[3,4-d]isoxazole-4,6-diones, pyrazolo[3,4-d]pyridazines and pyrazolo[1,5-a]pyrimidines
por: Zaki, Yasser Hassan, et al.
Publicado: (2016)

Synthesis of Highly Substituted Oxazoles through Iodine(III)-Mediated Reactions of Ketones with Nitriles
por: Saito, Akio, et al.
Publicado: (2012)

Pyrazole-based lamellarin O analogues: synthesis, biological evaluation and structure–activity relationships
por: Dzedulionytė, Karolina, et al.
Publicado: (2023)

10-Methyl-2-oxo-4-phenyl-2,11-dihydropyrano[2,3-a]carbazole-3-carbonitrile
por: Thiruvalluvar, A., et al.
Publicado: (2013)

5-(4-Chlorophenyl)-1-methyl-3-phenyl-3,6,8,9-tetrahydropyrazolo[3,4-b]thiopyrano[4,3-d]pyridine
por: Jia, Runhong, et al.
Publicado: (2011)

Tautomeric-Dependent Lactam Cycloaddition with Nitrile Oxide: Facile Synthesis of 1,2,4-Oxadiazole[4,5-a]indolone Derivatives
por: Jiang, Kun-Ming, et al.
Publicado: (2017)

Synthesis of Bicyclic Isoxazoles and Isoxazolines via Intramolecular Nitrile Oxide Cycloaddition
por: Chen, Wen-Chang, et al.
Publicado: (2015)

A straightforward conversion of 1,4-quinones into polycyclic pyrazoles via [3 + 2]-cycloaddition with fluorinated nitrile imines
por: Utecht-Jarzyńska, Greta, et al.
Publicado: (2021)

Green One Pot Solvent-Free Synthesis of Pyrano[2,3-c]-Pyrazoles and Pyrazolo[1,5-a]Pyrimidines
por: Al-Matar, Hamad M., et al.
Publicado: (2010)

6-Amino-3-methyl-4-(3,4,5-trimethoxyphenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
por: Sharma, Naresh, et al.
Publicado: (2014)

2-Amino-4-(4-methoxyphenyl)-5-oxo-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile acetic acid monosolvate
por: Chakraborty, Bimal Bhushan, et al.
Publicado: (2023)

Aryl nitrile oxide cycloaddition reactions in the presence of pinacol boronic acid ester
por: Harding, Sarah L, et al.
Publicado: (2012)

Crystal structure of 3-methyl-1-phenyl-6-propylamino-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile
por: Jasinski, Jerry P., et al.
Publicado: (2015)

Nitrile Oxide, Alkenes, Dipolar Cycloaddition, Isomerization and Metathesis Involved in the Syntheses of 2-Isoxazolines
por: Krompiec, Stanisław, et al.
Publicado: (2023)

Regioselective Synthesis of 5-Trifluoromethyl 1,2,4-Triazoles via [3 + 2]-Cycloaddition of Nitrile Imines with CF(3)CN
por: Lin, Bo, et al.
Publicado: (2022)

A convenient four-component one-pot strategy toward the synthesis of pyrazolo[3,4-d]pyrimidines
por: Liu, Mingxing, et al.
Publicado: (2015)

Efficient synthesis of spirooxindolyl oxazol-2(5H)-ones via palladium(ii)-catalyzed addition of arylboronic acids to nitriles
por: Song, Hao, et al.
Publicado: (2019)

4-Nitrophthalonitrile
por: Jan, Chin Yee, et al.
Publicado: (2014)

[3 + 2]-Cycloadditions of nitrile ylides after photoactivation of vinyl azides under flow conditions
por: Cludius-Brandt, Stephan, et al.
Publicado: (2013)

Total Synthesis of (−)-Mitrephorone A Enabled by Stereoselective Nitrile Oxide Cycloaddition and Tetrasubstituted Olefin Synthesis
por: Schneider, Michael, et al.
Publicado: (2020)

Nitrileimines as an alternative to azides in base-mediated click [3 + 2] cycloaddition with methylene active nitriles
por: Tupychak, Mykola A., et al.
Publicado: (2020)

Regioselective Cycloaddition of Nitrile Imines to 5-Methylidene-3-phenyl-hydantoin: Synthesis and DFT Calculations
por: Filkina, Maria E., et al.
Publicado: (2023)

An unusual thionyl chloride-promoted C−C bond formation to obtain 4,4'-bipyrazolones
por: Eller, Gernot A, et al.
Publicado: (2018)

Crystal structure of 6-amino-4-(3-bromo-4-methoxyphenyl)-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile dimethyl sulfoxide monosolvate
por: Yousuf, Sammer, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_gsmnvb1o91mpld6f8o99dfaip7