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Características clínicas y factores de riesgo de mortalidad en menores de 18 años con COVID-19 en México y Ciudad de México
INTRODUCTION: In the paediatric population, coronavirus disease (COVID-19) is usually asymptomatic or mild, but there are also severe and fatal cases. METHODS: We analysed data on COVID-19 cases from the national and state-level databases of the Federal Ministry of Health of Mexico and the Departmen...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Asociación Española de Pediatría. Published by Elsevier España, S.L.U.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469217/ https://www.ncbi.nlm.nih.gov/pubmed/34603458 http://dx.doi.org/10.1016/j.anpedi.2021.07.014 |
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author | Wong-Chew, Rosa María Noyola, Daniel Ernesto Villa, Antonio Rafael |
author_facet | Wong-Chew, Rosa María Noyola, Daniel Ernesto Villa, Antonio Rafael |
author_sort | Wong-Chew, Rosa María |
collection | PubMed |
description | INTRODUCTION: In the paediatric population, coronavirus disease (COVID-19) is usually asymptomatic or mild, but there are also severe and fatal cases. METHODS: We analysed data on COVID-19 cases from the national and state-level databases of the Federal Ministry of Health of Mexico and the Department of Health of Mexico City to determine the clinical characteristics and risk factors for mortality in children. We used Cox proportional hazards regression analysis to calculate the risk of death. RESULTS: The national and Mexico City databases had recorded a total of 18,465 (2.8%) and 5,733 (4.2%) confirmed cases of COVID-19, respectively, in individuals aged less than 18 years as of September 2020. The median age at diagnosis was 12 years (range: 0–17). The differences between cases in the national vs Mexico City databases were: 12.5% vs 8.2% of patients were hospitalised; 6% vs 3.5% had pneumonia; 2.4% vs 1.9% were admitted to the intensive care unit (ICU), and 1.3% vs 0.7% died. The independent risk factors significantly associated with a higher probability of death were pneumonia, hypertension, obesity, immunosuppression and intubation. CONCLUSION: In Mexico, 2.8% of all confirmed cases of COVID-19 occurred in individuals under 18 years, with a median age of 12 years and a mortality of 1.3%. The identified predictors of mortality were pneumonia, admission to the ICU, obesity, hypertension, immunosuppression, diabetes, chronic lung disease and renal disease. |
format | Online Article Text |
id | pubmed-8469217 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Asociación Española de Pediatría. Published by Elsevier España, S.L.U. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84692172021-09-27 Características clínicas y factores de riesgo de mortalidad en menores de 18 años con COVID-19 en México y Ciudad de México Wong-Chew, Rosa María Noyola, Daniel Ernesto Villa, Antonio Rafael An Pediatr (Barc) Original INTRODUCTION: In the paediatric population, coronavirus disease (COVID-19) is usually asymptomatic or mild, but there are also severe and fatal cases. METHODS: We analysed data on COVID-19 cases from the national and state-level databases of the Federal Ministry of Health of Mexico and the Department of Health of Mexico City to determine the clinical characteristics and risk factors for mortality in children. We used Cox proportional hazards regression analysis to calculate the risk of death. RESULTS: The national and Mexico City databases had recorded a total of 18,465 (2.8%) and 5,733 (4.2%) confirmed cases of COVID-19, respectively, in individuals aged less than 18 years as of September 2020. The median age at diagnosis was 12 years (range: 0–17). The differences between cases in the national vs Mexico City databases were: 12.5% vs 8.2% of patients were hospitalised; 6% vs 3.5% had pneumonia; 2.4% vs 1.9% were admitted to the intensive care unit (ICU), and 1.3% vs 0.7% died. The independent risk factors significantly associated with a higher probability of death were pneumonia, hypertension, obesity, immunosuppression and intubation. CONCLUSION: In Mexico, 2.8% of all confirmed cases of COVID-19 occurred in individuals under 18 years, with a median age of 12 years and a mortality of 1.3%. The identified predictors of mortality were pneumonia, admission to the ICU, obesity, hypertension, immunosuppression, diabetes, chronic lung disease and renal disease. Asociación Española de Pediatría. Published by Elsevier España, S.L.U. 2022-08 2021-09-27 /pmc/articles/PMC8469217/ /pubmed/34603458 http://dx.doi.org/10.1016/j.anpedi.2021.07.014 Text en © 2021 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Original Wong-Chew, Rosa María Noyola, Daniel Ernesto Villa, Antonio Rafael Características clínicas y factores de riesgo de mortalidad en menores de 18 años con COVID-19 en México y Ciudad de México |
title | Características clínicas y factores de riesgo de mortalidad en menores de 18 años con COVID-19 en México y Ciudad de México |
title_full | Características clínicas y factores de riesgo de mortalidad en menores de 18 años con COVID-19 en México y Ciudad de México |
title_fullStr | Características clínicas y factores de riesgo de mortalidad en menores de 18 años con COVID-19 en México y Ciudad de México |
title_full_unstemmed | Características clínicas y factores de riesgo de mortalidad en menores de 18 años con COVID-19 en México y Ciudad de México |
title_short | Características clínicas y factores de riesgo de mortalidad en menores de 18 años con COVID-19 en México y Ciudad de México |
title_sort | características clínicas y factores de riesgo de mortalidad en menores de 18 años con covid-19 en méxico y ciudad de méxico |
topic | Original |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469217/ https://www.ncbi.nlm.nih.gov/pubmed/34603458 http://dx.doi.org/10.1016/j.anpedi.2021.07.014 |
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