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Increased Autotaxin Levels in Severe COVID-19, Correlating with IL-6 Levels, Endothelial Dysfunction Biomarkers, and Impaired Functions of Dendritic Cells

Autotaxin (ATX; ENPP2) is a secreted lysophospholipase D catalyzing the extracellular production of lysophosphatidic acid (LPA), a pleiotropic signaling phospholipid. Genetic and pharmacologic studies have previously established a pathologic role for ATX and LPA signaling in pulmonary injury, inflam...

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Autores principales:	Nikitopoulou, Ioanna, Fanidis, Dionysios, Ntatsoulis, Konstantinos, Moulos, Panagiotis, Mpekoulis, George, Evangelidou, Maria, Vassiliou, Alice G., Dimakopoulou, Vasiliki, Jahaj, Edison, Tsipilis, Stamatios, Orfanos, Stylianos E., Dimopoulou, Ioanna, Angelakis, Emmanouil, Akinosoglou, Karolina, Vassilaki, Niki, Tzouvelekis, Argyrios, Kotanidou, Anastasia, Aidinis, Vassilis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469279/ https://www.ncbi.nlm.nih.gov/pubmed/34576169 http://dx.doi.org/10.3390/ijms221810006

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