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Aryl Hydrocarbon Receptor and Cysteine Redox Dynamics Underlie (Mal)adaptive Mechanisms to Chronic Intermittent Hypoxia in Kidney Cortex

We hypothesized that an interplay between aryl hydrocarbon receptor (AhR) and cysteine-related thiolome at the kidney cortex underlies the mechanisms of (mal)adaptation to chronic intermittent hypoxia (CIH), promoting arterial hypertension (HTN). Using a rat model of CIH-HTN, we investigated the imp...

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Detalles Bibliográficos
Autores principales: Correia, Maria João, Pimpão, António B., Lopes-Coelho, Filipa, Sequeira, Catarina O., Coelho, Nuno R., Gonçalves-Dias, Clara, Barouki, Robert, Coumoul, Xavier, Serpa, Jacinta, Morello, Judit, Monteiro, Emília C., Pereira, Sofia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469308/
https://www.ncbi.nlm.nih.gov/pubmed/34573115
http://dx.doi.org/10.3390/antiox10091484