Wharton’s Jelly-Derived Mesenchymal Stem Cells Reduce Fibrosis in a Mouse Model of Duchenne Muscular Dystrophy by Upregulating microRNA 499

The aim of this study was to evaluate the therapeutic effects and mechanisms of Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) in an animal model of Duchenne muscular dystrophy (DMD). Mdx mice (3–5 months old) were administered five different doses of WJ-MSCs through their tail veins. A we...

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Detalles Bibliográficos
Autores principales: Park, Sang Eon, Jeong, Jang Bin, Oh, Shin Ji, Kim, Sun Jeong, Kim, Hyeongseop, Choi, Alee, Choi, Suk-joo, Oh, Soo-young, Ryu, Gyu Ha, Lee, Jeehun, Jeon, Hong Bae, Chang, Jong Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469349/
https://www.ncbi.nlm.nih.gov/pubmed/34572277
http://dx.doi.org/10.3390/biomedicines9091089

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