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Hyaluronic Acid-Binding, Anionic, Nanoparticles Inhibit ECM Degradation and Restore Compressive Stiffness in Aggrecan-Depleted Articular Cartilage Explants

Joint trauma results in the production of inflammatory cytokines that stimulate the secretion of catabolic enzymes, which degrade articular cartilage. Molecular fragments of the degraded articular cartilage further stimulate inflammatory cytokine production, with this process eventually resulting in...

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Detalles Bibliográficos
Autores principales:	Deloney, Marcus, Garoosi, Parssa, Dartora, Vanessa F. C., Christiansen, Blaine A., Panitch, Alyssa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469381/ https://www.ncbi.nlm.nih.gov/pubmed/34575579 http://dx.doi.org/10.3390/pharmaceutics13091503

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