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Comprehensive Evidence of Carrier-Mediated Distribution of Amantadine to the Retina across the Blood–Retinal Barrier in Rats

Amantadine, a drug used for the blockage of NMDA receptors, is well-known to exhibit neuroprotective effects. Accordingly, assessment of amantadine transport at retinal barriers could result in the application of amantadine for retinal diseases such as glaucoma. The objective of this study was to el...

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Detalles Bibliográficos
Autores principales: Shinozaki, Yusuke, Akanuma, Shin-ichi, Mori, Yuika, Kubo, Yoshiyuki, Hosoya, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469395/
https://www.ncbi.nlm.nih.gov/pubmed/34575415
http://dx.doi.org/10.3390/pharmaceutics13091339

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