Cargando…

RNA-Sequencing Based microRNA Expression Signature of Colorectal Cancer: The Impact of Oncogenic Targets Regulated by miR-490-3p

To elucidate novel aspects of the molecular pathogenesis of colorectal cancer (CRC), we have created a new microRNA (miRNA) expression signature based on RNA-sequencing. Analysis of the signature showed that 84 miRNAs were upregulated, and 70 were downregulated in CRC tissues. Interestingly, our sig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hozaka, Yuto, Kita, Yoshiaki, Yasudome, Ryutaro, Tanaka, Takako, Wada, Masumi, Idichi, Tetsuya, Tanabe, Kan, Asai, Shunichi, Moriya, Shogo, Toda, Hiroko, Mori, Shinichiro, Kurahara, Hiroshi, Ohtsuka, Takao, Seki, Naohiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469425/ https://www.ncbi.nlm.nih.gov/pubmed/34576039 http://dx.doi.org/10.3390/ijms22189876

Ejemplares similares

Molecular Pathogenesis of Colorectal Cancer: Impact of Oncogenic Targets Regulated by Tumor Suppressive miR-139-3p
por: Yasudome, Ryutaro, et al.
Publicado: (2022)

Role of miR-30a-3p Regulation of Oncogenic Targets in Pancreatic Ductal Adenocarcinoma Pathogenesis
por: Shimomura, Hiroki, et al.
Publicado: (2020)

Molecular Pathogenesis and Regulation of the miR-29-3p-Family: Involvement of ITGA6 and ITGB1 in Intra-Hepatic Cholangiocarcinoma
por: Hozaka, Yuto, et al.
Publicado: (2021)

Molecular Pathogenesis of Pancreatic Ductal Adenocarcinoma: Impact of miR-30c-5p and miR-30c-2-3p Regulation on Oncogenic Genes
por: Tanaka, Takako, et al.
Publicado: (2020)

Coronin 1C, Regulated by Multiple microRNAs, Facilitates Cancer Cell Aggressiveness in Pancreatic Ductal Adenocarcinoma
por: Fukuda, Kosuke, et al.
Publicado: (2023)

Curative resection after chemotherapy and chemoradiotherapy for postoperative recurrence of pancreatic tail cancer in the abdominal wall: a case report
por: Iio, Shunya, et al.
Publicado: (2022)

Oncogenic Targets Regulated by Tumor-Suppressive miR-30c-1-3p and miR-30c-2-3p: TRIP13 Facilitates Cancer Cell Aggressiveness in Breast Cancer
por: Mitsueda, Reiko, et al.
Publicado: (2023)

RNA‐sequence‐based microRNA expression signature in breast cancer: tumor‐suppressive miR‐101‐5p regulates molecular pathogenesis
por: Toda, Hiroko, et al.
Publicado: (2019)

Gene Regulation by Antitumor miR-204-5p in Pancreatic Ductal Adenocarcinoma: The Clinical Significance of Direct RACGAP1 Regulation
por: Khalid, Muhammad, et al.
Publicado: (2019)

ZFP36L2 promotes cancer cell aggressiveness and is regulated by antitumor microRNA‐375 in pancreatic ductal adenocarcinoma
por: Yonemori, Keiichi, et al.
Publicado: (2017)

Postoperative recurrence with right cervical lymph node metastasis in hepatocellular carcinoma: a case report
por: Tanoue, Kiyonori, et al.
Publicado: (2021)

Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports
por: Tanoue, Kiyonori, et al.
Publicado: (2022)

The microRNA expression signature of pancreatic ductal adenocarcinoma by RNA sequencing: anti-tumour functions of the microRNA-216 cluster
por: Yonemori, Keiichi, et al.
Publicado: (2017)

Involvement of anti-tumor miR-124-3p and its targets in the pathogenesis of pancreatic ductal adenocarcinoma: direct regulation of ITGA3 and ITGB1 by miR-124-3p
por: Idichi, Tetsuya, et al.
Publicado: (2018)

Molecular pathogenesis of pancreatic ductal adenocarcinoma: Impact of passenger strand of pre‐miR‐148a on gene regulation
por: Idichi, Tetsuya, et al.
Publicado: (2018)

Clinical Benefits of Conversion Surgery for Unresectable Pancreatic Ductal Adenocarcinoma: A Single-Institution, Retrospective Analysis
por: Mataki, Yuko, et al.
Publicado: (2021)

Retroperitoneal schwannoma sandwiched between abdominal aorta and inferior vena cava. A case report
por: Nepal, Pramod, et al.
Publicado: (2020)

Locally advanced cholangiolocellular carcinoma successfully treated with curative resection after downsizing chemotherapy: a case report
por: Hozaka, Yuto, et al.
Publicado: (2021)

Regulation of actin-binding protein ANLN by antitumor miR-217 inhibits cancer cell aggressiveness in pancreatic ductal adenocarcinoma
por: Idichi, Tetsuya, et al.
Publicado: (2017)

Usefulness of (18)F-fluorodeoxyglucose-positron emission tomography/computed tomography in primary cystadenocarcinoma of the mesentery: a case report
por: Hozaka, Yuto, et al.
Publicado: (2020)

MicroRNA-490-3p and −490-5p in carcinogenesis: Separate or the same goal?
por: Li, Yin, et al.
Publicado: (2021)

Clinical prospects for laparoscopic stoma closure of a temporary loop ileostomy: Initial experience and report
por: Kita, Yoshiaki, et al.
Publicado: (2020)

Regulation of Oncogenic Targets by the Tumor-Suppressive miR-139 Duplex (miR-139-5p and miR-139-3p) in Renal Cell Carcinoma
por: Okada, Reona, et al.
Publicado: (2020)

Regulation of MMP13 by antitumor microRNA-375 markedly inhibits cancer cell migration and invasion in esophageal squamous cell carcinoma
por: Osako, Yusaku, et al.
Publicado: (2016)

Recurrent gastric cancer sustaining a partial response after the nivolumab discontinuation because of immune-related adverse events: a case report
por: Arigami, Takaaki, et al.
Publicado: (2020)

Modified Delta-shaped Anastomosis via the Overlap Method Using Linear Staplers for Colon Cancer
por: Nepal, Pramod, et al.
Publicado: (2021)

Multiple liver metastases with synchronous gastric and transverse colon cancer diagnosed by gastric perforation successfully treated by SOX plus bevacizumab and completely resected by surgery: a case report
por: Matsumoto, Ryu, et al.
Publicado: (2020)

MicroRNA-490 inhibits tumorigenesis and progression in breast cancer
por: Zhao, Lin, et al.
Publicado: (2016)

Clinical Utility and Limitation of Diagnostic Ability for Different Degrees of Dysplasia of Intraductal Papillary Mucinous Neoplasms of the Pancreas Using (18)F-Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography
por: Hozaka, Yuto, et al.
Publicado: (2021)

Conversion surgery for stage IV gastric cancer with a complete pathological response to nivolumab: a case report
por: Matsumoto, Ryu, et al.
Publicado: (2020)

Successful treatment of post chemotherapy esophageal cicatricial atresia in a pediatric patient with anaplastic large cell lymphoma through minimally invasive esophagectomy: a case report
por: Hozaka, Yuto, et al.
Publicado: (2021)

FAM64A: A Novel Oncogenic Target of Lung Adenocarcinoma Regulated by Both Strands of miR-99a (miR-99a-5p and miR-99a-3p)
por: Mizuno, Keiko, et al.
Publicado: (2020)

Successful treatment for severe pancreatitis with colonic perforation using video-assisted retroperitoneal debridement: A case report
por: Hozaka, Yuto, et al.
Publicado: (2018)

Identification of Tumor Suppressive Genes Regulated by miR-31-5p and miR-31-3p in Head and Neck Squamous Cell Carcinoma
por: Oshima, Sachi, et al.
Publicado: (2021)

Colorectal Cancer Patients Have Four Specific Bacterial Species in Oral and Gut Microbiota in Common—A Metagenomic Comparison with Healthy Subjects
por: Uchino, Yoshinori, et al.
Publicado: (2021)

A prognostic scoring system for conversion surgery after trastuzumab-based chemotherapy for human epidermal growth factor receptor 2-positive advanced gastric cancer
por: Arigami, Takaaki, et al.
Publicado: (2022)

Three-stage laparoscopic surgery in a morbidly obese patient with Hinchey III diverticulitis: a case report
por: Tanaka, Takako, et al.
Publicado: (2019)

miRNA-490-3p promotes the metastatic progression of invasive ductal carcinoma
por: Lu, Ning, et al.
Publicado: (2021)

Impact of Oncogenic Targets by Tumor-Suppressive miR-139-5p and miR-139-3p Regulation in Head and Neck Squamous Cell Carcinoma
por: Koma, Ayaka, et al.
Publicado: (2021)

Regulation of Oncogenic Targets by Tumor-Suppressive miR-150-3p in Lung Squamous Cell Carcinoma
por: Mizuno, Keiko, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vrh48p7jvesuauf72l7rvp9r6s