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Pre-Clinical Pharmacokinetic Characterization, Tissue Distribution, and Excretion Studies of Novel Edaravone Oral Prodrug, TEJ-1704

Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) is a free radical scavenger approved for the treatment of amyotrophic lateral sclerosis, a fatal neuromuscular disease. Edaravone is administered as an intravenous infusion over 60 min for several treatment cycles. To ease the burden of patients and ca...

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Detalles Bibliográficos
Autores principales:	Kang, Dong Wook, Kim, Ju Hee, Kim, Kyung Min, Cho, Seok-jin, Jang, Hee-Woon, Chang, Ji Won, Dong, Seung Myung, Lim, Jee Woong, Kim, Jae-Sun, Cho, Hea-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469431/ https://www.ncbi.nlm.nih.gov/pubmed/34575481 http://dx.doi.org/10.3390/pharmaceutics13091406

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