From the Evasion of Degradation to Ubiquitin-Dependent Protein Stabilization

A hallmark of cancer is dysregulated protein turnover (proteostasis), which involves pathologic ubiquitin-dependent degradation of tumor suppressor proteins, as well as increased oncoprotein stabilization. The latter is due, in part, to mutation within sequences, termed degrons, which are required f...

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Detalles Bibliográficos
Autores principales: Abu Ahmad, Yamen, Oknin-Vaisman, Avital, Bitman-Lotan, Eliya, Orian, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469536/
https://www.ncbi.nlm.nih.gov/pubmed/34572023
http://dx.doi.org/10.3390/cells10092374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469536/
https://www.ncbi.nlm.nih.gov/pubmed/34572023
http://dx.doi.org/10.3390/cells10092374

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