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Endogenous Regulation and Pharmacological Modulation of Sepsis-Induced HMGB1 Release and Action: An Updated Review

Sepsis remains a common cause of death in intensive care units, accounting for approximately 20% of total deaths worldwide. Its pathogenesis is partly attributable to dysregulated inflammatory responses to bacterial endotoxins (such as lipopolysaccharide, LPS), which stimulate innate immune cells to...

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Detalles Bibliográficos
Autores principales: Zhu, Cassie Shu, Wang, Wei, Qiang, Xiaoling, Chen, Weiqiang, Lan, Xiqian, Li, Jianhua, Wang, Haichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469563/
https://www.ncbi.nlm.nih.gov/pubmed/34571869
http://dx.doi.org/10.3390/cells10092220