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Deciphering Repertoire of B16 Melanoma Reactive TCRs by Immunization, In Vitro Restimulation and Sequencing of IFNγ-Secreting T Cells

Recent advances in cancer immunotherapy have great promise for the treatment of solid tumors. One of the key limiting factors that hamper the decoding of physiological responses to these therapies is the inability to distinguish between specific and nonspecific responses. The identification of tumor...

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Detalles Bibliográficos
Autores principales: Izosimova, Anna V., Yuzhakova, Diana V., Skatova, Valeria D., Volchkova, Lilia N., Zagainova, Elena V., Chudakov, Dmitry M., Sharonov, George V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469664/
https://www.ncbi.nlm.nih.gov/pubmed/34576023
http://dx.doi.org/10.3390/ijms22189859