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What Are the Factors Associated with Nonadherence to Medications in Patients with Chronic Diseases?

Introduction: Adherence to medications is very crucial for an optimized clinical outcome in the management of chronic diseases. Beliefs about medications and other factors can significantly affect adherence to chronic medications. The objective of the present research was to identify the associated...

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Autores principales: Al Bawab, Abdel Qader, Al-Qerem, Walid, Abusara, Osama, Alkhatib, Nimer, Mansour, Maha, Horne, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469667/
https://www.ncbi.nlm.nih.gov/pubmed/34575011
http://dx.doi.org/10.3390/healthcare9091237
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author Al Bawab, Abdel Qader
Al-Qerem, Walid
Abusara, Osama
Alkhatib, Nimer
Mansour, Maha
Horne, Robert
author_facet Al Bawab, Abdel Qader
Al-Qerem, Walid
Abusara, Osama
Alkhatib, Nimer
Mansour, Maha
Horne, Robert
author_sort Al Bawab, Abdel Qader
collection PubMed
description Introduction: Adherence to medications is very crucial for an optimized clinical outcome in the management of chronic diseases. Beliefs about medications and other factors can significantly affect adherence to chronic medications. The objective of the present research was to identify the associated factors of adherence to medication in Jordanian patients with chronic diseases utilizing a stepwise binary logistical regression model. Methods: A cross-sectional study was carried out between November 2018 and March 2020. The participants were reached from secondary and tertiary care setting clinics in Jordan. The recruited patients were asked to report their attitudes of adherence to medications and beliefs about medications via filling out the MARS-5 and BMQ-specific tools. Sociodemographic data were also collected from the recruited patients and included in the regression model. A stepwise binary logistical regression model was applied to identify the associated factors of adherence to chronic medications in the tested sample. Results: A total of 485 patients who met the inclusion criteria were recruited. The mean age of the participants was 57.14 (age ranged from 22 to 82 years). Around 39% of the participants were older than 65 years. Most of the patients were either hypertensive or diabetic (35.7% and 32.2%, respectively). The logistic regression model indicated that necessity beliefs are strongly associated with adherence (OR 4.22), while concerns beliefs, dosage frequency and having medical insurance were negatively associated with adherence (OR 0.73, 0.74 and 0.26, respectively), with a p-value ≤ 0.05. Conclusions: Both the MARS-5 and BMQ-specific questionnaires were applied successfully on the tested sample. Better attention should be paid to the logistic regression model variables that were associated with adherence in order to guarantee optimal treatment outcomes in the treatment of chronic diseases.
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spelling pubmed-84696672021-09-27 What Are the Factors Associated with Nonadherence to Medications in Patients with Chronic Diseases? Al Bawab, Abdel Qader Al-Qerem, Walid Abusara, Osama Alkhatib, Nimer Mansour, Maha Horne, Robert Healthcare (Basel) Article Introduction: Adherence to medications is very crucial for an optimized clinical outcome in the management of chronic diseases. Beliefs about medications and other factors can significantly affect adherence to chronic medications. The objective of the present research was to identify the associated factors of adherence to medication in Jordanian patients with chronic diseases utilizing a stepwise binary logistical regression model. Methods: A cross-sectional study was carried out between November 2018 and March 2020. The participants were reached from secondary and tertiary care setting clinics in Jordan. The recruited patients were asked to report their attitudes of adherence to medications and beliefs about medications via filling out the MARS-5 and BMQ-specific tools. Sociodemographic data were also collected from the recruited patients and included in the regression model. A stepwise binary logistical regression model was applied to identify the associated factors of adherence to chronic medications in the tested sample. Results: A total of 485 patients who met the inclusion criteria were recruited. The mean age of the participants was 57.14 (age ranged from 22 to 82 years). Around 39% of the participants were older than 65 years. Most of the patients were either hypertensive or diabetic (35.7% and 32.2%, respectively). The logistic regression model indicated that necessity beliefs are strongly associated with adherence (OR 4.22), while concerns beliefs, dosage frequency and having medical insurance were negatively associated with adherence (OR 0.73, 0.74 and 0.26, respectively), with a p-value ≤ 0.05. Conclusions: Both the MARS-5 and BMQ-specific questionnaires were applied successfully on the tested sample. Better attention should be paid to the logistic regression model variables that were associated with adherence in order to guarantee optimal treatment outcomes in the treatment of chronic diseases. MDPI 2021-09-20 /pmc/articles/PMC8469667/ /pubmed/34575011 http://dx.doi.org/10.3390/healthcare9091237 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Al Bawab, Abdel Qader
Al-Qerem, Walid
Abusara, Osama
Alkhatib, Nimer
Mansour, Maha
Horne, Robert
What Are the Factors Associated with Nonadherence to Medications in Patients with Chronic Diseases?
title What Are the Factors Associated with Nonadherence to Medications in Patients with Chronic Diseases?
title_full What Are the Factors Associated with Nonadherence to Medications in Patients with Chronic Diseases?
title_fullStr What Are the Factors Associated with Nonadherence to Medications in Patients with Chronic Diseases?
title_full_unstemmed What Are the Factors Associated with Nonadherence to Medications in Patients with Chronic Diseases?
title_short What Are the Factors Associated with Nonadherence to Medications in Patients with Chronic Diseases?
title_sort what are the factors associated with nonadherence to medications in patients with chronic diseases?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469667/
https://www.ncbi.nlm.nih.gov/pubmed/34575011
http://dx.doi.org/10.3390/healthcare9091237
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