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Success of Thrombectomy in Management of Ischemic Stroke in Two Patients with SynCardia Total Artificial Heart in Bridge-to-Transplantation

Introduction: Circulatory assistance from a SynCardia Total Artificial Heart (SynCardia-TAH) is a reliable bridge-to-transplant solution for patients with end-stage biventricular heart failure. Ischemic strokes affect about 10% of patients with a SynCardia-TAH. We report for the first time in the li...

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Autores principales: Le Picault, Brendan, David, Charles-Henri, Alexandre, Pierre-Louis, Lenoble, Cédric, Bizouarn, Philippe, Lepoivre, Thierry, Groleau, Nicolas, Rozec, Bertrand, Desal, Hubert, Roussel, Jean-Christian, Sénage, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469750/
https://www.ncbi.nlm.nih.gov/pubmed/34562948
http://dx.doi.org/10.3390/bioengineering8090126
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author Le Picault, Brendan
David, Charles-Henri
Alexandre, Pierre-Louis
Lenoble, Cédric
Bizouarn, Philippe
Lepoivre, Thierry
Groleau, Nicolas
Rozec, Bertrand
Desal, Hubert
Roussel, Jean-Christian
Sénage, Thomas
author_facet Le Picault, Brendan
David, Charles-Henri
Alexandre, Pierre-Louis
Lenoble, Cédric
Bizouarn, Philippe
Lepoivre, Thierry
Groleau, Nicolas
Rozec, Bertrand
Desal, Hubert
Roussel, Jean-Christian
Sénage, Thomas
author_sort Le Picault, Brendan
collection PubMed
description Introduction: Circulatory assistance from a SynCardia Total Artificial Heart (SynCardia-TAH) is a reliable bridge-to-transplant solution for patients with end-stage biventricular heart failure. Ischemic strokes affect about 10% of patients with a SynCardia-TAH. We report for the first time in the literature two successful thrombectomies to treat the acute phase of ischemic stroke in two patients treated with a SynCardia-TAH in the bridge-to-transplant (BTT). Case report: We follow two patients with circulatory support from a SynCardia-TAH in the bridge-to-transplant for terminal biventricular cardiac failure with ischemic stroke during the support period. An early in-hospital diagnosis enables the completion of a mechanical thrombectomy within the first 6 h of the onset of symptoms. There was no intracranial hemorrhagic complication during or after the procedure and the patients fully recovered from neurological deficits, allowing a successful heart transplant. Conclusion: This case report describes the possibility of treating ischemic strokes under a SynCardia-TAH by mechanical thrombectomy following the same recommendations as for the general population with excellent results and without any hemorrhagic complication during or after the procedure.
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spelling pubmed-84697502021-09-27 Success of Thrombectomy in Management of Ischemic Stroke in Two Patients with SynCardia Total Artificial Heart in Bridge-to-Transplantation Le Picault, Brendan David, Charles-Henri Alexandre, Pierre-Louis Lenoble, Cédric Bizouarn, Philippe Lepoivre, Thierry Groleau, Nicolas Rozec, Bertrand Desal, Hubert Roussel, Jean-Christian Sénage, Thomas Bioengineering (Basel) Case Report Introduction: Circulatory assistance from a SynCardia Total Artificial Heart (SynCardia-TAH) is a reliable bridge-to-transplant solution for patients with end-stage biventricular heart failure. Ischemic strokes affect about 10% of patients with a SynCardia-TAH. We report for the first time in the literature two successful thrombectomies to treat the acute phase of ischemic stroke in two patients treated with a SynCardia-TAH in the bridge-to-transplant (BTT). Case report: We follow two patients with circulatory support from a SynCardia-TAH in the bridge-to-transplant for terminal biventricular cardiac failure with ischemic stroke during the support period. An early in-hospital diagnosis enables the completion of a mechanical thrombectomy within the first 6 h of the onset of symptoms. There was no intracranial hemorrhagic complication during or after the procedure and the patients fully recovered from neurological deficits, allowing a successful heart transplant. Conclusion: This case report describes the possibility of treating ischemic strokes under a SynCardia-TAH by mechanical thrombectomy following the same recommendations as for the general population with excellent results and without any hemorrhagic complication during or after the procedure. MDPI 2021-09-19 /pmc/articles/PMC8469750/ /pubmed/34562948 http://dx.doi.org/10.3390/bioengineering8090126 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Le Picault, Brendan
David, Charles-Henri
Alexandre, Pierre-Louis
Lenoble, Cédric
Bizouarn, Philippe
Lepoivre, Thierry
Groleau, Nicolas
Rozec, Bertrand
Desal, Hubert
Roussel, Jean-Christian
Sénage, Thomas
Success of Thrombectomy in Management of Ischemic Stroke in Two Patients with SynCardia Total Artificial Heart in Bridge-to-Transplantation
title Success of Thrombectomy in Management of Ischemic Stroke in Two Patients with SynCardia Total Artificial Heart in Bridge-to-Transplantation
title_full Success of Thrombectomy in Management of Ischemic Stroke in Two Patients with SynCardia Total Artificial Heart in Bridge-to-Transplantation
title_fullStr Success of Thrombectomy in Management of Ischemic Stroke in Two Patients with SynCardia Total Artificial Heart in Bridge-to-Transplantation
title_full_unstemmed Success of Thrombectomy in Management of Ischemic Stroke in Two Patients with SynCardia Total Artificial Heart in Bridge-to-Transplantation
title_short Success of Thrombectomy in Management of Ischemic Stroke in Two Patients with SynCardia Total Artificial Heart in Bridge-to-Transplantation
title_sort success of thrombectomy in management of ischemic stroke in two patients with syncardia total artificial heart in bridge-to-transplantation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469750/
https://www.ncbi.nlm.nih.gov/pubmed/34562948
http://dx.doi.org/10.3390/bioengineering8090126
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