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P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells
P-Rex1 is a guanine-nucleotide exchange factor (GEF) that activates Rac-type small G proteins in response to the stimulation of a range of receptors, particularly G protein-coupled receptors (GPCRs), to control cytoskeletal dynamics and other Rac-dependent cell responses. P-Rex1 is mainly expressed...
Autores principales: | Hampson, Elizabeth, Tsonou, Elpida, Baker, Martin J., Hornigold, David C., Hubbard, Roderick E., Massey, Andrew, Welch, Heidi C. E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469755/ https://www.ncbi.nlm.nih.gov/pubmed/34572121 http://dx.doi.org/10.3390/cells10092474 |
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