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Continuous Feeding Reduces the Generation of Metabolic Byproducts and Increases Antibodies Expression in Chinese Hamster Ovary-K1 Cells

Chinese hamster ovary (CHO) cells are the most important host system used for monoclonal antibody (mAb) expression. Moreover, the fed-batch culture mode is the most widely used method to increase mAb expression in CHO cells by increasing the amount of feed. However, a high amount of culture feed res...

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Detalles Bibliográficos
Autores principales: Xiao, Shang, Ahmed, Waqas, Mohsin, Ali, Guo, Meijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469772/
https://www.ncbi.nlm.nih.gov/pubmed/34575094
http://dx.doi.org/10.3390/life11090945