Cargando…

Hypertensive Patients Exhibit Enhanced Thrombospondin-1 Levels at High-Altitude

Thrombospondin-1 (THBS1) levels elevate under hypoxia and have relevance in several cardiovascular disorders. The association of THBS1 with endothelial dysfunction implies its important role in hypertension. To establish the hypothesis, we screened patients with hypertension and their respective con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sharma, Kavita, Chanana, Neha, Mohammad, Ghulam, Thinlas, Tashi, Gupta, Mohit, Syed, Mansoor Ali, Das, Rajat Subhra, Pasha, Qadar, Mishra, Aastha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469964/ https://www.ncbi.nlm.nih.gov/pubmed/34575042 http://dx.doi.org/10.3390/life11090893

Ejemplares similares

Differential methylation in EGLN1 associates with blood oxygen saturation and plasma protein levels in high-altitude pulmonary edema
por: Sharma, Kavita, et al.
Publicado: (2022)

Dexamethasone prophylaxis protects from acute high-altitude illness by modifying the peripheral blood mononuclear cell inflammatory transcriptome
por: Kumar, Rahul, et al.
Publicado: (2023)

The Telomere-Telomerase System Is Detrimental to Health at High-Altitude
por: Pasha, Qadar, et al.
Publicado: (2023)

Interactions among Vascular-Tone Modulators Contribute to High Altitude Pulmonary Edema and Augmented Vasoreactivity in Highlanders
por: Ali, Zahara, et al.
Publicado: (2012)

The EDN1 Missense Variant rs5370G > T Regulates Adaptation and Maladaptation under Hypobaric Hypoxia
por: Palmo, Tsering, et al.
Publicado: (2022)

Disparities in COVID-19 incidence and fatality rates at high-altitude
por: Abbasi, Bilal Ahmed, et al.
Publicado: (2023)

Sexual Dimorphism of Dexamethasone as a Prophylactic Treatment in Pathologies Associated With Acute Hypobaric Hypoxia Exposure
por: Chanana, Neha, et al.
Publicado: (2022)

Vascular homeostasis at high-altitude: role of genetic variants and transcription factors
por: Chanana, Neha, et al.
Publicado: (2020)

ROCK2 and MYLK variants under hypobaric hypoxic environment of high altitude associate with high altitude pulmonary edema and adaptation
por: Pandey, Priyanka, et al.
Publicado: (2015)

Elevated blood plasma levels of epinephrine, norepinephrine, tyrosine hydroxylase, TGFβ1, and TNFα associated with high-altitude pulmonary edema in an Indian population
por: Pandey, Priyanka, et al.
Publicado: (2016)

Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Genetics of pulmonary hypertension
por: Pasha, Qadar
Publicado: (2014)

Molecular Mechanisms of High-Altitude Acclimatization
por: Mallet, Robert T., et al.
Publicado: (2023)

Interactions between the FTO and GNB3 Genes Contribute to Varied Clinical Phenotypes in Hypertension
por: Kumar, Rahul, et al.
Publicado: (2013)

Association of GNB3 C825T polymorphism with plasma electrolyte balance and susceptibility to hypertension
por: Nejatizadeh, Azim, et al.
Publicado: (2011)

The role of circulating thrombospondin-1 in patients with precapillary pulmonary hypertension
por: Kaiser, Ralf, et al.
Publicado: (2016)

Thrombospondins and synaptogenesis★
por: Wang, Bin, et al.
Publicado: (2012)

Role of thrombospondin-1 and thrombospondin-2 in cardiovascular diseases (Review)
por: Zhang, Kaijie, et al.
Publicado: (2020)

High-altitude and low-altitude adapted chicken gut-microbes have different functional diversity
por: Bhagat, Neha Rani, et al.
Publicado: (2023)

Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension
por: Ochoa, Cristhiaan D, et al.
Publicado: (2010)

Thrombospondin-4 is a putative tumour-suppressor gene in colorectal cancer that exhibits age-related methylation
por: Greco, Sonia A, et al.
Publicado: (2010)

Identification and characterization of thrombospondin-4, a new member of the thrombospondin gene family
Publicado: (1993)

Modulation of the extracellular matrix patterning of thrombospondins by actin dynamics and thrombospondin oligomer state
por: Hellewell, Andrew L., et al.
Publicado: (2015)

Blood Picture of Indians at High Altitudes
por: Gupta, C. R. Das
Publicado: (1952)

Tumor necrosis factor-alpha −308G/A gene polymorphism and novel biomarker profiles in patients with Takayasu arteritis
por: Sarkar, Prattay Guha, et al.
Publicado: (2018)

Susceptibility of CTLA-4 −1661A/G polymorphism towards severity of rheumatic heart disease
por: Bansal, Ankit, et al.
Publicado: (2021)

Hiccups and Slurring of Speech: Atypical Presentation of High-Altitude Cerebral Edema
por: Kaeley, Nidhi, et al.
Publicado: (2023)

Thrombospondins function as regulators of angiogenesis
por: Bornstein, Paul
Publicado: (2009)

The Roles of Thrombospondins in Hemorrhagic Stroke
por: Wu, Xuan, et al.
Publicado: (2017)

Thrombospondins and remodeling of the tumor microenvironment
por: Stenina-Adognravi, Olga, et al.
Publicado: (2018)

Thrombospondin 1 in Metabolic Diseases
por: Gutierrez, Linda S., et al.
Publicado: (2021)

Distinct Features of Gut Microbiota in High-Altitude Tibetan and Middle-Altitude Han Hypertensive Patients
por: Zhu, Lu-lu, et al.
Publicado: (2020)

Association of altitude and urbanization with hypertension and obesity: analysis of the Nepal Demographic and Health Survey 2016
por: Mehata, Suresh, et al.
Publicado: (2020)

Thrombospondin-1 proteomimetic polymers exhibit anti-angiogenic activity in a neovascular age-related macular degeneration mouse model
por: Choi, Wonmin, et al.
Publicado: (2023)

A Study on the Molecular Mechanism of High Altitude Heart Disease in Children
por: Tashi, Qu-Zhen, et al.
Publicado: (2022)

Thrombospondin stimulates motility of human neutrophils
Publicado: (1990)

Thrombospondin: synthesis and secretion by cells in culture
Publicado: (1982)

Thrombospondin-1: Multiple Paths to Inflammation
por: Lopez-Dee, Zenaida, et al.
Publicado: (2011)

The interaction of Thrombospondins with extracellular matrix proteins
por: Tan, Kemin, et al.
Publicado: (2009)

Thrombospondins: A Role in Cardiovascular Disease
por: Chistiakov, Dimitry A., et al.
Publicado: (2017)

Functions of Thrombospondin-1 in the Tumor Microenvironment
por: Kaur, Sukhbir, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_nepmfkavcqr9v5d1qrh76v94us