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Evolution of CD8(+) T Cell Receptor (TCR) Engineered Therapies for the Treatment of Cancer

Engineered T cell receptor T (TCR-T) cell therapy has facilitated the generation of increasingly reliable tumor antigen-specific adaptable cellular products for the treatment of human cancer. TCR-T cell therapies were initially focused on targeting shared tumor-associated peptide targets, including...

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Detalles Bibliográficos
Autores principales: Sun, Yimo, Li, Fenge, Sonnemann, Heather, Jackson, Kyle R., Talukder, Amjad H., Katailiha, Arjun S., Lizee, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469972/
https://www.ncbi.nlm.nih.gov/pubmed/34572028
http://dx.doi.org/10.3390/cells10092379