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In Vitro and In Vivo Evaluation of Oral Controlled Release Formulation of BCS Class I Drug Using Polymer Matrix System

Diltiazem hydrochloride is a calcium channel blocker, which belongs to the family of benzothiazepines. It is commonly used to treat hypertension and atrial fibrillation. Even though the drug has high solubility, its high permeability and rapid metabolism in the liver can limit the bioavailability an...

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Detalles Bibliográficos
Autores principales:	Arafat, Mosab, Sarfraz, Muhammad, Bostanudin, Mohammad F., Esmaeil, Anna, Salam, Aisha, AbuRuz, Salahdein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470007/ https://www.ncbi.nlm.nih.gov/pubmed/34577629 http://dx.doi.org/10.3390/ph14090929

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