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Assessing Lymphatic Uptake of Lipids Using Magnetic Resonance Imaging: A Feasibility Study in Healthy Human Volunteers with Potential Application for Tracking Lymph Node Delivery of Drugs and Formulation Excipients

Dietary lipids and some pharmaceutical lipid excipients can facilitate the targeted delivery of drugs to the intestinal lymphatics. Here, the feasibility of magnetic resonance imaging (MRI) for imaging lipid uptake into the intestinal lymphatics was assessed, shedding light on which lymph nodes can...

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Detalles Bibliográficos
Autores principales: Jewell, Adelaide, Williams, Hannah, Hoad, Caroline L., Gellert, Paul R., Ashford, Marianne B., Butler, James, Stolnik, Snow, Scurr, David, Stocks, Michael J., Marciani, Luca, Gowland, Penny A., Gershkovich, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470042/
https://www.ncbi.nlm.nih.gov/pubmed/34575420
http://dx.doi.org/10.3390/pharmaceutics13091343