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DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility

In this paper, the results on the fabrication of ferroelectric membranes as vascular patches with modified surfaces are presented. For the modification of a membrane surface contacting blood, DLC coating was deposited using the pulsed vacuum arc deposition technique. The physico-chemical properties...

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Autores principales: Yuriev, Yuri, Goreninskii, Semen, Runts, Artem, Prosetskaya, Elisaveta, Plotnikov, Evgenii, Shishkova, Darya, Kudryavtseva, Yulia, Bolbasov, Evgeny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470059/
https://www.ncbi.nlm.nih.gov/pubmed/34564507
http://dx.doi.org/10.3390/membranes11090690
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author Yuriev, Yuri
Goreninskii, Semen
Runts, Artem
Prosetskaya, Elisaveta
Plotnikov, Evgenii
Shishkova, Darya
Kudryavtseva, Yulia
Bolbasov, Evgeny
author_facet Yuriev, Yuri
Goreninskii, Semen
Runts, Artem
Prosetskaya, Elisaveta
Plotnikov, Evgenii
Shishkova, Darya
Kudryavtseva, Yulia
Bolbasov, Evgeny
author_sort Yuriev, Yuri
collection PubMed
description In this paper, the results on the fabrication of ferroelectric membranes as vascular patches with modified surfaces are presented. For the modification of a membrane surface contacting blood, DLC coating was deposited using the pulsed vacuum arc deposition technique. The physico-chemical properties and cytotoxicity of the membranes modified under various conditions were studied. It was found that DLC coatings do not affect membrane microstructure, preserving its crystal structure as well as its high strength and elongation. It was revealed that an increase in the capacitor storage voltage results in the rise in sp(2)- and sp-hybridized carbon concentration, which makes it possible to control the chemical structure and surface energy of the modified surface. The experiments with 3T3L1 fibroblasts showed no toxic effects of the materials extracts.
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spelling pubmed-84700592021-09-27 DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility Yuriev, Yuri Goreninskii, Semen Runts, Artem Prosetskaya, Elisaveta Plotnikov, Evgenii Shishkova, Darya Kudryavtseva, Yulia Bolbasov, Evgeny Membranes (Basel) Article In this paper, the results on the fabrication of ferroelectric membranes as vascular patches with modified surfaces are presented. For the modification of a membrane surface contacting blood, DLC coating was deposited using the pulsed vacuum arc deposition technique. The physico-chemical properties and cytotoxicity of the membranes modified under various conditions were studied. It was found that DLC coatings do not affect membrane microstructure, preserving its crystal structure as well as its high strength and elongation. It was revealed that an increase in the capacitor storage voltage results in the rise in sp(2)- and sp-hybridized carbon concentration, which makes it possible to control the chemical structure and surface energy of the modified surface. The experiments with 3T3L1 fibroblasts showed no toxic effects of the materials extracts. MDPI 2021-09-07 /pmc/articles/PMC8470059/ /pubmed/34564507 http://dx.doi.org/10.3390/membranes11090690 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yuriev, Yuri
Goreninskii, Semen
Runts, Artem
Prosetskaya, Elisaveta
Plotnikov, Evgenii
Shishkova, Darya
Kudryavtseva, Yulia
Bolbasov, Evgeny
DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility
title DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility
title_full DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility
title_fullStr DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility
title_full_unstemmed DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility
title_short DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility
title_sort dlc-coated ferroelectric membranes as vascular patches: physico-chemical properties and biocompatibility
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470059/
https://www.ncbi.nlm.nih.gov/pubmed/34564507
http://dx.doi.org/10.3390/membranes11090690
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