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VKNG-1 Antagonizes ABCG2-Mediated Multidrug Resistance via p-AKT and Bcl-2 Pathway in Colon Cancer: In Vitro and In Vivo Study

SIMPLE SUMMARY: Multidrug resistance or chemoresistance is a phenomenon where cells exhibit resistance to drugs that are pharmacologically and structurally distinct. ABCG2, a member of ABC transporter superfamily has been widely reported to be a principal cause of MDR in various cancers via pumping...

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Detalles Bibliográficos
Autores principales: Narayanan, Silpa, Fan, Ying-Fang, Gujarati, Nehaben A., Teng, Qiu-Xu, Wang, Jing-Quan, Cai, Chao-Yun, Yang, Yuqi, Chintalapati, Anirudh J., Lei, Yixiong, Korlipara, Vijaya L., Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470077/
https://www.ncbi.nlm.nih.gov/pubmed/34572902
http://dx.doi.org/10.3390/cancers13184675