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Preliminary Study on Light-Activated Antimicrobial Agents as Photocatalytic Method for Protection of Surfaces with Increased Risk of Infections

Preventing and controlling the spread of multidrug-resistant (MDR) bacteria implicated in healthcare-associated infections is the greatest challenge of the health systems. In recent decades, research has shown the need for passive antibacterial protection of surfaces in order to reduce the microbial...

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Autores principales: Bucuresteanu, Razvan, Ditu, Lia-Mara, Ionita, Monica, Calinescu, Ioan, Raditoiu, Valentin, Cojocaru, Bogdan, Cinteza, Ludmila Otilia, Curutiu, Carmen, Holban, Alina Maria, Enachescu, Marius, Enache, Laura-Bianca, Mustatea, Gabriel, Chihaia, Viorel, Nicolaev, Adela, Borcan, Elena-Larisa, Mihaescu, Grigore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470258/
https://www.ncbi.nlm.nih.gov/pubmed/34576531
http://dx.doi.org/10.3390/ma14185307
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author Bucuresteanu, Razvan
Ditu, Lia-Mara
Ionita, Monica
Calinescu, Ioan
Raditoiu, Valentin
Cojocaru, Bogdan
Cinteza, Ludmila Otilia
Curutiu, Carmen
Holban, Alina Maria
Enachescu, Marius
Enache, Laura-Bianca
Mustatea, Gabriel
Chihaia, Viorel
Nicolaev, Adela
Borcan, Elena-Larisa
Mihaescu, Grigore
author_facet Bucuresteanu, Razvan
Ditu, Lia-Mara
Ionita, Monica
Calinescu, Ioan
Raditoiu, Valentin
Cojocaru, Bogdan
Cinteza, Ludmila Otilia
Curutiu, Carmen
Holban, Alina Maria
Enachescu, Marius
Enache, Laura-Bianca
Mustatea, Gabriel
Chihaia, Viorel
Nicolaev, Adela
Borcan, Elena-Larisa
Mihaescu, Grigore
author_sort Bucuresteanu, Razvan
collection PubMed
description Preventing and controlling the spread of multidrug-resistant (MDR) bacteria implicated in healthcare-associated infections is the greatest challenge of the health systems. In recent decades, research has shown the need for passive antibacterial protection of surfaces in order to reduce the microbial load and microbial biofilm development, frequently associated with transmission of infections. The aim of the present study is to analyze the efficiency of photocatalytic antimicrobial protection methods of surfaces using the new photocatalytic paint activated by light in the visible spectrum. The new composition is characterized by a wide range of analytical methods, such as UV-VIS spectroscopy, electron microscopy (SEM), X-ray powder diffraction (PXRD) or X-ray photoelectron spectroscopy (XPS). The photocatalytic activity in the UV-A was compared with the one in the visible light spectrum using an internal method developed on the basis of DIN 52980: 2008-10 standard and ISO 10678—2010 standard. Migration of metal ions in the composition was tested based on SR EN1186-3: 2003 standard. The new photocatalytic antimicrobial method uses a type of photocatalytic paint that is active in the visible spectral range and generates reactive oxygen species with inhibitory effect against all tested microbial strains.
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spelling pubmed-84702582021-09-27 Preliminary Study on Light-Activated Antimicrobial Agents as Photocatalytic Method for Protection of Surfaces with Increased Risk of Infections Bucuresteanu, Razvan Ditu, Lia-Mara Ionita, Monica Calinescu, Ioan Raditoiu, Valentin Cojocaru, Bogdan Cinteza, Ludmila Otilia Curutiu, Carmen Holban, Alina Maria Enachescu, Marius Enache, Laura-Bianca Mustatea, Gabriel Chihaia, Viorel Nicolaev, Adela Borcan, Elena-Larisa Mihaescu, Grigore Materials (Basel) Article Preventing and controlling the spread of multidrug-resistant (MDR) bacteria implicated in healthcare-associated infections is the greatest challenge of the health systems. In recent decades, research has shown the need for passive antibacterial protection of surfaces in order to reduce the microbial load and microbial biofilm development, frequently associated with transmission of infections. The aim of the present study is to analyze the efficiency of photocatalytic antimicrobial protection methods of surfaces using the new photocatalytic paint activated by light in the visible spectrum. The new composition is characterized by a wide range of analytical methods, such as UV-VIS spectroscopy, electron microscopy (SEM), X-ray powder diffraction (PXRD) or X-ray photoelectron spectroscopy (XPS). The photocatalytic activity in the UV-A was compared with the one in the visible light spectrum using an internal method developed on the basis of DIN 52980: 2008-10 standard and ISO 10678—2010 standard. Migration of metal ions in the composition was tested based on SR EN1186-3: 2003 standard. The new photocatalytic antimicrobial method uses a type of photocatalytic paint that is active in the visible spectral range and generates reactive oxygen species with inhibitory effect against all tested microbial strains. MDPI 2021-09-14 /pmc/articles/PMC8470258/ /pubmed/34576531 http://dx.doi.org/10.3390/ma14185307 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bucuresteanu, Razvan
Ditu, Lia-Mara
Ionita, Monica
Calinescu, Ioan
Raditoiu, Valentin
Cojocaru, Bogdan
Cinteza, Ludmila Otilia
Curutiu, Carmen
Holban, Alina Maria
Enachescu, Marius
Enache, Laura-Bianca
Mustatea, Gabriel
Chihaia, Viorel
Nicolaev, Adela
Borcan, Elena-Larisa
Mihaescu, Grigore
Preliminary Study on Light-Activated Antimicrobial Agents as Photocatalytic Method for Protection of Surfaces with Increased Risk of Infections
title Preliminary Study on Light-Activated Antimicrobial Agents as Photocatalytic Method for Protection of Surfaces with Increased Risk of Infections
title_full Preliminary Study on Light-Activated Antimicrobial Agents as Photocatalytic Method for Protection of Surfaces with Increased Risk of Infections
title_fullStr Preliminary Study on Light-Activated Antimicrobial Agents as Photocatalytic Method for Protection of Surfaces with Increased Risk of Infections
title_full_unstemmed Preliminary Study on Light-Activated Antimicrobial Agents as Photocatalytic Method for Protection of Surfaces with Increased Risk of Infections
title_short Preliminary Study on Light-Activated Antimicrobial Agents as Photocatalytic Method for Protection of Surfaces with Increased Risk of Infections
title_sort preliminary study on light-activated antimicrobial agents as photocatalytic method for protection of surfaces with increased risk of infections
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470258/
https://www.ncbi.nlm.nih.gov/pubmed/34576531
http://dx.doi.org/10.3390/ma14185307
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