Cargando…

Mitochondrial Heterogeneity in Metabolic Diseases

SIMPLE SUMMARY: Often times mitochondria within a single cell are depicted as homogenous entities both morphologically and functionally. In normal and diseased states, mitochondria are heterogeneous and display distinct functional properties. In both cases, mitochondria exhibit differences in morpho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ngo, Jennifer, Osto, Corey, Villalobos, Frankie, Shirihai, Orian S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470264/ https://www.ncbi.nlm.nih.gov/pubmed/34571805 http://dx.doi.org/10.3390/biology10090927

Ejemplares similares

Mitochondrial oxidative function in NAFLD: Friend or foe?
por: Shum, Michael, et al.
Publicado: (2020)

Mitochondrial signal transduction
por: Picard, Martin, et al.
Publicado: (2022)

Utilization of Human Samples for Assessment of Mitochondrial Bioenergetics: Gold Standards, Limitations, and Future Perspectives
por: Acin-Perez, Rebeca, et al.
Publicado: (2021)

Initial B Cell Activation Induces Metabolic Reprogramming and Mitochondrial Remodeling
por: Waters, Lynnea R., et al.
Publicado: (2018)

Optimal Dynamics for Quality Control in Spatially Distributed Mitochondrial Networks
por: Patel, Pinkesh K., et al.
Publicado: (2013)

A novel approach to measure complex V ATP hydrolysis in frozen cell lysates and tissue homogenates
por: Fernandez-del-Rio, Lucia, et al.
Publicado: (2023)

Cellular Star Trek: A laser-based shuttle transfers mitochondria into cells
por: Las, Guy, et al.
Publicado: (2016)

Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet‐Induced Metabolic Heart Disease
por: Sverdlov, Aaron L., et al.
Publicado: (2016)

DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer
por: Shen, Ning, et al.
Publicado: (2021)

MitoTimer probe reveals the impact of autophagy, fusion, and motility on subcellular distribution of young and old mitochondrial protein and on relative mitochondrial protein age
por: Ferree, Andrew W, et al.
Publicado: (2013)

The mitochondrial fission protein Drp1 in liver is required to mitigate NASH and prevents the activation of the mitochondrial ISR
por: Steffen, Janos, et al.
Publicado: (2022)

TNFα-Induced Oxidative Stress and Mitochondrial Dysfunction Alter Hypothalamic Neurogenesis and Promote Appetite Versus Satiety Neuropeptide Expression in Mice
por: Desai, Mina, et al.
Publicado: (2022)

Mitochondrial heterogeneity in diseases
por: Chen, Long, et al.
Publicado: (2023)

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell
por: Deeney, Jude T., et al.
Publicado: (2016)

Insulin Signaling Regulates Mitochondrial Function in Pancreatic β-Cells
por: Liu, Siming, et al.
Publicado: (2009)

ATP Binding and Hydrolysis Properties of ABCB10 and Their Regulation by Glutathione
por: Qiu, Wei, et al.
Publicado: (2015)

Testosterone Plus Low-Intensity Physical Training in Late Life Improves Functional Performance, Skeletal Muscle Mitochondrial Biogenesis, and Mitochondrial Quality Control in Male Mice
por: Guo, Wen, et al.
Publicado: (2012)

Erythroid Differentiation and Heme Biosynthesis Are Dependent on a Shift in the Balance of Mitochondrial Fusion and Fission Dynamics
por: Gonzalez-Ibanez, Alvaro M., et al.
Publicado: (2020)

Modulation of mTOR signaling as a strategy for the treatment of Pompe disease
por: Lim, Jeong‐A, et al.
Publicado: (2017)

Isolation and functional analysis of peridroplet mitochondria from murine brown adipose tissue
por: Ngo, Jennifer, et al.
Publicado: (2020)

Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes
por: Moore, Timothy M., et al.
Publicado: (2022)

Mitochondrial Networking Protects β-Cells From Nutrient-Induced Apoptosis
por: Molina, Anthony J.A., et al.
Publicado: (2009)

IRGM1 links mitochondrial quality control to autoimmunity
por: Rai, Prashant, et al.
Publicado: (2021)

ATP-consuming futile cycles as energy dissipating mechanisms to counteract obesity
por: Brownstein, Alexandra J., et al.
Publicado: (2021)

A new target for an old DUB: UCH-L1 regulates mitofusin-2 levels, altering mitochondrial morphology, function and calcium uptake
por: Cerqueira, Fernanda M., et al.
Publicado: (2020)

Metabolic reprogramming heterogeneity in chronic kidney disease
por: Miguel, Verónica, et al.
Publicado: (2023)

Reactive Oxygen Species Stimulate Insulin Secretion in Rat Pancreatic Islets: Studies Using Mono-Oleoyl-Glycerol
por: Saadeh, Marylana, et al.
Publicado: (2012)

Mutations in LRRK2 potentiate age-related impairment of autophagic flux
por: Saha, Shamol, et al.
Publicado: (2015)

The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis
por: Acevedo, Aracely, et al.
Publicado: (2023)

Mitochondrial Heterogeneity: Evaluating Mitochondrial Subpopulation Dynamics in Stem Cells
por: Woods, D. C.
Publicado: (2017)

Mitochondrial Ataxias: Molecular Classification and Clinical Heterogeneity
por: Lopriore, Piervito, et al.
Publicado: (2022)

Mitochondrial Heterogeneity
por: Aryaman, Juvid, et al.
Publicado: (2019)

Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure
por: Wikstrom, Jakob D, et al.
Publicado: (2014)

Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease
por: Zeng, Jialiu, et al.
Publicado: (2023)

Mitochondrial Metabolism in Major Neurological Diseases
por: Zhou, Zhengqiu, et al.
Publicado: (2018)

High Density Lipoproteins: Metabolism, Function, and Therapeutic Potential
por: Jomard, Anne, et al.
Publicado: (2020)

Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl‐CoA
por: Ngo, Jennifer, et al.
Publicado: (2023)

Heterogeneity of Mitochondria and Mitochondrial Function within Cells as Another Level of Mitochondrial Complexity
por: Kuznetsov, Andrey V, et al.
Publicado: (2009)

Altered TDP-43 Structure and Function: Key Insights into Aberrant RNA, Mitochondrial, and Cellular and Systemic Metabolism in Amyotrophic Lateral Sclerosis
por: Jiang, Leanne, et al.
Publicado: (2022)

Imaging metabolic heterogeneity in cancer
por: Sengupta, Debanti, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_3mdhdokaf5jjide2srrpfhupge