In Vitro Miniaturized Tuberculosis Spheroid Model

Tuberculosis (TB) is a public health concern that impacts 10 million people around the world. Current in vitro models are low throughput and/or lack caseation, which impairs drug effectiveness in humans. Here, we report the generation of THP-1 human monocyte/macrophage spheroids housing mycobacteria...

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Detalles Bibliográficos
Autores principales: Mukundan, Shilpaa, Singh, Pooja, Shah, Aditi, Kumar, Ranjeet, O’Neill, Kelly C., Carter, Claire L., Russell, David G., Subbian, Selvakumar, Parekkadan, Biju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470281/
https://www.ncbi.nlm.nih.gov/pubmed/34572395
http://dx.doi.org/10.3390/biomedicines9091209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470281/
https://www.ncbi.nlm.nih.gov/pubmed/34572395
http://dx.doi.org/10.3390/biomedicines9091209

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