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In Vitro Miniaturized Tuberculosis Spheroid Model
Tuberculosis (TB) is a public health concern that impacts 10 million people around the world. Current in vitro models are low throughput and/or lack caseation, which impairs drug effectiveness in humans. Here, we report the generation of THP-1 human monocyte/macrophage spheroids housing mycobacteria...
Autores principales: | Mukundan, Shilpaa, Singh, Pooja, Shah, Aditi, Kumar, Ranjeet, O’Neill, Kelly C., Carter, Claire L., Russell, David G., Subbian, Selvakumar, Parekkadan, Biju |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470281/ https://www.ncbi.nlm.nih.gov/pubmed/34572395 http://dx.doi.org/10.3390/biomedicines9091209 |
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