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Storage of Mutant Human SOD1 in Non-Neural Cells from the Type-1 Amyotrophic Lateral Sclerosis rat(G93A) Model Correlated with the Lysosomes’ Dysfunction

Herein, we explored the impact of the lysosome dysfunction during the progression of Amyotrophic Lateral Sclerosis type-1 (ALS1). We conducted the study in non-neural cells, primary fibroblasts (rFFFs), and bone marrow-mesenchymal stem cells (rBM-MSCs), isolated from the animal model rat(G93A) for A...

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Detalles Bibliográficos
Autores principales:	Bicchi, Ilaria, Morena, Francesco, Argentati, Chiara, Nodari, Laura Rota, Emiliani, Carla, Gelati, Maurizio, Vescovi, Angelo L., Martino, Sabata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470315/ https://www.ncbi.nlm.nih.gov/pubmed/34572266 http://dx.doi.org/10.3390/biomedicines9091080

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