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Convenient Genetic Encoding of Phenylalanine Derivatives through Their α-Keto Acid Precursors

The activity and function of proteins can be improved by incorporation of non-canonical amino acids (ncAAs). To avoid the tedious synthesis of a large number of chiral phenylalanine derivatives, we synthesized the corresponding phenylpyruvic acid precursors. Escherichia coli strain DH10B and strain...

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Detalles Bibliográficos
Autores principales: Liu, Li, Wang, Bohao, Li, Sheng, Xu, Fengyuan, He, Qi, Pan, Chun, Gao, Xiangdong, Yao, Wenbing, Song, Xiaoda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470325/
https://www.ncbi.nlm.nih.gov/pubmed/34572570
http://dx.doi.org/10.3390/biom11091358