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Surgical Management of Hereditary Breast Cancer
The identification that breast cancer is hereditary was first described in the nineteenth century. With the identification of the BRCA1 and BRCA 2 breast/ovarian cancer susceptibility genes in the mid-1990s and the introduction of genetic testing, significant advancements have been made in tailoring...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470490/ https://www.ncbi.nlm.nih.gov/pubmed/34573353 http://dx.doi.org/10.3390/genes12091371 |
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author | Berger, Elizabeth R. Golshan, Mehra |
author_facet | Berger, Elizabeth R. Golshan, Mehra |
author_sort | Berger, Elizabeth R. |
collection | PubMed |
description | The identification that breast cancer is hereditary was first described in the nineteenth century. With the identification of the BRCA1 and BRCA 2 breast/ovarian cancer susceptibility genes in the mid-1990s and the introduction of genetic testing, significant advancements have been made in tailoring surveillance, guiding decisions on medical or surgical risk reduction and cancer treatments for genetic variant carriers. This review discusses various medical and surgical management options for hereditary breast cancers. |
format | Online Article Text |
id | pubmed-8470490 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84704902021-09-27 Surgical Management of Hereditary Breast Cancer Berger, Elizabeth R. Golshan, Mehra Genes (Basel) Review The identification that breast cancer is hereditary was first described in the nineteenth century. With the identification of the BRCA1 and BRCA 2 breast/ovarian cancer susceptibility genes in the mid-1990s and the introduction of genetic testing, significant advancements have been made in tailoring surveillance, guiding decisions on medical or surgical risk reduction and cancer treatments for genetic variant carriers. This review discusses various medical and surgical management options for hereditary breast cancers. MDPI 2021-08-31 /pmc/articles/PMC8470490/ /pubmed/34573353 http://dx.doi.org/10.3390/genes12091371 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Berger, Elizabeth R. Golshan, Mehra Surgical Management of Hereditary Breast Cancer |
title | Surgical Management of Hereditary Breast Cancer |
title_full | Surgical Management of Hereditary Breast Cancer |
title_fullStr | Surgical Management of Hereditary Breast Cancer |
title_full_unstemmed | Surgical Management of Hereditary Breast Cancer |
title_short | Surgical Management of Hereditary Breast Cancer |
title_sort | surgical management of hereditary breast cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470490/ https://www.ncbi.nlm.nih.gov/pubmed/34573353 http://dx.doi.org/10.3390/genes12091371 |
work_keys_str_mv | AT bergerelizabethr surgicalmanagementofhereditarybreastcancer AT golshanmehra surgicalmanagementofhereditarybreastcancer |