Cargando…
Mechanosensitivity in Pulmonary Circulation: Pathophysiological Relevance of Stretch-Activated Channels in Pulmonary Hypertension
A variety of cell types in pulmonary arteries (endothelial cells, fibroblasts, and smooth muscle cells) are continuously exposed to mechanical stimulations such as shear stress and pulsatile blood pressure, which are altered under conditions of pulmonary hypertension (PH). Most functions of such vas...
Autores principales: | Barbeau, Solène, Gilbert, Guillaume, Cardouat, Guillaume, Baudrimont, Isabelle, Freund-Michel, Véronique, Guibert, Christelle, Marthan, Roger, Vacher, Pierre, Quignard, Jean-François, Ducret, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470538/ https://www.ncbi.nlm.nih.gov/pubmed/34572602 http://dx.doi.org/10.3390/biom11091389 |
Ejemplares similares
-
Piezo1 Channel Activation Reverses Pulmonary Artery Vasoconstriction in an Early Rat Model of Pulmonary Hypertension: The Role of Ca(2+) Influx and Akt-eNOS Pathway
por: Porto Ribeiro, Thais, et al.
Publicado: (2022) -
Cell Confluence Modulates TRPV4 Channel Activity in Response to Hypoxia
por: Barbeau, Solène, et al.
Publicado: (2022) -
Inflammation and Oxidative Stress Induce NGF Secretion by Pulmonary Arterial Cells through a TGF-β1-Dependent Mechanism
por: Bouchet, Clément, et al.
Publicado: (2022) -
NiONP-Induced Oxidative Stress and Mitochondrial Impairment in an In Vitro Pulmonary Vascular Cell Model Mimicking Endothelial Dysfunction
por: Germande, Ophélie, et al.
Publicado: (2022) -
Altered vasoreactivity in neonatal rats with pulmonary hypertension associated with bronchopulmonary dysplasia: Implication of both eNOS phosphorylation and calcium signaling
por: Dumas de la Roque, Eric, et al.
Publicado: (2017)