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The Effects of Two Nrf2 Activators, Bardoxolone Methyl and Omaveloxolone, on Retinal Ganglion Cell Survival during Ischemic Optic Neuropathy

Nonarteritic anterior ischemic optic neuropathy (NAION) is one of the most common acute optic neuropathies that affect the over 55-year-old population. NAION causes the loss of visual function, and it has no safe and effective therapy. Bardoxolone methyl (methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien...

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Detalles Bibliográficos
Autores principales: Chien, Jia-Ying, Chou, Yu-Yau, Ciou, Jhih-Wei, Liu, Fang-Yun, Huang, Shun-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470542/
https://www.ncbi.nlm.nih.gov/pubmed/34573098
http://dx.doi.org/10.3390/antiox10091466