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The Role of EUS-Guided FNA and FNB in Autoimmune Pancreatitis

Autoimmune pancreatitis (AIP) is an increasingly recognized disease classified into two different subtypes based on histology. According to the International Diagnostic Criteria (ICDC), the diagnosis is achieved using a combination of different criteria. In patients presenting with a typical imaging...

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Autores principales: de Pretis, Nicolò, Crinò, Stefano Francesco, Frulloni, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470670/
https://www.ncbi.nlm.nih.gov/pubmed/34573995
http://dx.doi.org/10.3390/diagnostics11091653
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author de Pretis, Nicolò
Crinò, Stefano Francesco
Frulloni, Luca
author_facet de Pretis, Nicolò
Crinò, Stefano Francesco
Frulloni, Luca
author_sort de Pretis, Nicolò
collection PubMed
description Autoimmune pancreatitis (AIP) is an increasingly recognized disease classified into two different subtypes based on histology. According to the International Diagnostic Criteria (ICDC), the diagnosis is achieved using a combination of different criteria. In patients presenting with a typical imaging appearance, the diagnosis may be straightforward, and steroid treatment is recommended, even without histological confirmation. In patients with atypical imaging or mass-forming appearance, the differential diagnosis with pancreatic cancer is challenging and crucial for treatment strategy. Endoscopic ultrasound (EUS)-guided tissue acquisition has been proposed to achieve a histological diagnosis. Fine-needle aspiration (FNA) was first proposed to aspirate cells from pancreatic lesions. Despite excellent results in terms of sensitivity for pancreatic cancer, the data are disappointing regarding the diagnosis of AIP. The recent development of new needles allowing fine-needle biopsy (FNB) has been associated with improved diagnostic accuracy based on preserving the tissue architecture, which is necessary to detect the typical histological features of AIP. However, the published literature on the role of EUS-guided FNA and FNB is limited and mainly focused on type 1 AIP. The present study aimed to review the available literature on the role of EUS-guided FNA and FNB in the diagnosis of AIP.
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spelling pubmed-84706702021-09-27 The Role of EUS-Guided FNA and FNB in Autoimmune Pancreatitis de Pretis, Nicolò Crinò, Stefano Francesco Frulloni, Luca Diagnostics (Basel) Review Autoimmune pancreatitis (AIP) is an increasingly recognized disease classified into two different subtypes based on histology. According to the International Diagnostic Criteria (ICDC), the diagnosis is achieved using a combination of different criteria. In patients presenting with a typical imaging appearance, the diagnosis may be straightforward, and steroid treatment is recommended, even without histological confirmation. In patients with atypical imaging or mass-forming appearance, the differential diagnosis with pancreatic cancer is challenging and crucial for treatment strategy. Endoscopic ultrasound (EUS)-guided tissue acquisition has been proposed to achieve a histological diagnosis. Fine-needle aspiration (FNA) was first proposed to aspirate cells from pancreatic lesions. Despite excellent results in terms of sensitivity for pancreatic cancer, the data are disappointing regarding the diagnosis of AIP. The recent development of new needles allowing fine-needle biopsy (FNB) has been associated with improved diagnostic accuracy based on preserving the tissue architecture, which is necessary to detect the typical histological features of AIP. However, the published literature on the role of EUS-guided FNA and FNB is limited and mainly focused on type 1 AIP. The present study aimed to review the available literature on the role of EUS-guided FNA and FNB in the diagnosis of AIP. MDPI 2021-09-09 /pmc/articles/PMC8470670/ /pubmed/34573995 http://dx.doi.org/10.3390/diagnostics11091653 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
de Pretis, Nicolò
Crinò, Stefano Francesco
Frulloni, Luca
The Role of EUS-Guided FNA and FNB in Autoimmune Pancreatitis
title The Role of EUS-Guided FNA and FNB in Autoimmune Pancreatitis
title_full The Role of EUS-Guided FNA and FNB in Autoimmune Pancreatitis
title_fullStr The Role of EUS-Guided FNA and FNB in Autoimmune Pancreatitis
title_full_unstemmed The Role of EUS-Guided FNA and FNB in Autoimmune Pancreatitis
title_short The Role of EUS-Guided FNA and FNB in Autoimmune Pancreatitis
title_sort role of eus-guided fna and fnb in autoimmune pancreatitis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470670/
https://www.ncbi.nlm.nih.gov/pubmed/34573995
http://dx.doi.org/10.3390/diagnostics11091653
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